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Indole diterpenoid synthetic studies...
~
Kurti, Laszlo.
Indole diterpenoid synthetic studies. Part I. Optimization of the synthetic sequence leading to the eastern hemisphere subtarget of nodulisporic acids A, D, and F. Part II. Construction of the highly strained CDEF parent tetracycle of nodulisporic acids A and B.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Indole diterpenoid synthetic studies. Part I. Optimization of the synthetic sequence leading to the eastern hemisphere subtarget of nodulisporic acids A, D, and F. Part II. Construction of the highly strained CDEF parent tetracycle of nodulisporic acids A and B.
作者:
Kurti, Laszlo.
面頁冊數:
699 p.
附註:
Adviser: Amos B. Smith, III.
附註:
Source: Dissertation Abstracts International, Volume: 67-07, Section: B, page: 3802.
Contained By:
Dissertation Abstracts International67-07B.
標題:
Chemistry, Organic.
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3225487
ISBN:
9780542799624
Indole diterpenoid synthetic studies. Part I. Optimization of the synthetic sequence leading to the eastern hemisphere subtarget of nodulisporic acids A, D, and F. Part II. Construction of the highly strained CDEF parent tetracycle of nodulisporic acids A and B.
Kurti, Laszlo.
Indole diterpenoid synthetic studies. Part I. Optimization of the synthetic sequence leading to the eastern hemisphere subtarget of nodulisporic acids A, D, and F. Part II. Construction of the highly strained CDEF parent tetracycle of nodulisporic acids A and B.
- 699 p.
Adviser: Amos B. Smith, III.
Thesis (Ph.D.)--University of Pennsylvania, 2006.
*Please refer to dissertation for diagrams.
ISBN: 9780542799624Subjects--Topical Terms:
193634
Chemistry, Organic.
Indole diterpenoid synthetic studies. Part I. Optimization of the synthetic sequence leading to the eastern hemisphere subtarget of nodulisporic acids A, D, and F. Part II. Construction of the highly strained CDEF parent tetracycle of nodulisporic acids A and B.
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Indole diterpenoid synthetic studies. Part I. Optimization of the synthetic sequence leading to the eastern hemisphere subtarget of nodulisporic acids A, D, and F. Part II. Construction of the highly strained CDEF parent tetracycle of nodulisporic acids A and B.
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Adviser: Amos B. Smith, III.
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Thesis (Ph.D.)--University of Pennsylvania, 2006.
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*Please refer to dissertation for diagrams.
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Chapter one of this dissertation gives an overview of the isolation and structure determination of nodulisporic acids and details their biological activity. Then the optimization of the synthetic sequence leading to the Eastern Hemisphere Subtarget of Nodulisporic Acids A, D and F is described.*
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Chapter two gives a detailed account of the development of a new modular indole synthesis using a sequential Stille cross-coupling/Buchwald-Hartwig Union/Cyclization tactic. The new modular indole synthesis was successfully applied for the preparation of several highly substituted and strained indoles, including the CDEF parent tetracycle of Nodulisporic Acids A and B.*
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