國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Proteases of infectious agents

Dunn, Ben M.

Proteases of infectious agents

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Proteases of infectious agentsedited by Ben M. Dunn.
其他作者:	Dunn, Ben M.
出版者:	San Diego, Calif. :Academic,c1999.
面頁冊數:	1 online resource (xvii, 282 p., [15] p. of col. plates) :ill. (some col.)
標題:	Microbial enzymes.
電子資源:	http://www.sciencedirect.com/science/book/9780124205109
ISBN:	9780124205109

Proteases of infectious agents
Proteases of infectious agents[electronic resource] /edited by Ben M. Dunn. - San Diego, Calif. :Academic,c1999. - 1 online resource (xvii, 282 p., [15] p. of col. plates) :ill. (some col.)

J. Erickson and M. Eissenstat, HIV Protease as a Target for the Design of Antiviral Agents for AIDS. -- C. Steink�uhler, A. Urbani, and R. De Francesco, Proteases of the Hepatitis C Virus. -- S. Abdel-Meguid and X. Qiu, Human Herpesvirus Proteases. -- C. Abad-Zapatero, R. Goldman, and K. Stewart, The Secreted Proteinases from Candida: Challenges for Structure-Aided Drug Design. -- M.N.G. James and E. Bergman, Proteolytic Enzymes of the Viruses of the Family Picornaviridae. -- C. Berry, Proteases as Drug Targets in the Treatment of Malaria. -- J. Cazzulo, Chagas Disease. -- H. Kido, Y. Chen, M. Murakami, Y. Beppu, and T. Towatari, Cellular Proteinases and Viral Infection: Influenza Virus, Sendai Virus, and HIV-1. -- M. Lively, Bacterial Type 1 Signal Peptidases. -- J.A. Garcia, M.R. Fern�andez-Fern�andez, and J.J. L�opez-Moya, Proteinases Involved in Plant Virus Genome Expression. -- Subject Index.

Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery.

ISBN: 9780124205109

Source: 79195:79195Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

280911
Microbial enzymes.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: QP609.P78 / P746 1999eb

Dewey Class. No.: 572/.76

National Agricultural Library Call No.: RC112 / .P76 1999

National Library of Medicine Call No.: 1999 F-117

Proteases of infectious agents
LDR:04679cmm 2200433Ia 4500 001 342486
005 20120813085808.0
006 m d
007 cr cn|||||||||
008 120925s1999 cauaf ob 001 0 eng d
019 $a 742284441
020 $a 9780124205109
020 $a 0124205100
020 $a 9786611025113
020 $a 6611025111
029 1 $a NZ1 $b 12432358
029 1 $a AU@ $b 000048130384
029 1 $a DEBBG $b BV039830346
035 $a ocn162128877
037 $a 79195:79195 $b Elsevier Science & Technology $n http://www.sciencedirect.com
040 $a OPELS $b eng $c OPELS $d OCLCQ $d IDEBK $d OCLCQ
049 $a NTYA
050 4 $a QP609.P78 $b P746 1999eb
060 4 $a 1999 F-117
060 4 $a QU 136 $b P96715 1999
070 $a RC112 $b .P76 1999
072 0 $a X300
072 0 $a X380
072 7 $a MJCJ $2 bicssc
082 0 4 $a 572/.76 $2 22
245 0 0 $a Proteases of infectious agents $h [electronic resource] / $c edited by Ben M. Dunn.
260 $a San Diego, Calif. : $b Academic, $c c1999.
300 $a 1 online resource (xvii, 282 p., [15] p. of col. plates) : $b ill. (some col.)
505 0 $a J. Erickson and M. Eissenstat, HIV Protease as a Target for the Design of Antiviral Agents for AIDS. -- C. Steink�uhler, A. Urbani, and R. De Francesco, Proteases of the Hepatitis C Virus. -- S. Abdel-Meguid and X. Qiu, Human Herpesvirus Proteases. -- C. Abad-Zapatero, R. Goldman, and K. Stewart, The Secreted Proteinases from Candida: Challenges for Structure-Aided Drug Design. -- M.N.G. James and E. Bergman, Proteolytic Enzymes of the Viruses of the Family Picornaviridae. -- C. Berry, Proteases as Drug Targets in the Treatment of Malaria. -- J. Cazzulo, Chagas Disease. -- H. Kido, Y. Chen, M. Murakami, Y. Beppu, and T. Towatari, Cellular Proteinases and Viral Infection: Influenza Virus, Sendai Virus, and HIV-1. -- M. Lively, Bacterial Type 1 Signal Peptidases. -- J.A. Garcia, M.R. Fern�andez-Fern�andez, and J.J. L�opez-Moya, Proteinases Involved in Plant Virus Genome Expression. -- Subject Index.
505 0 0 $t HIV protease as a target for the design of antiviral agents for AIDS / $r John W. Erickson, Michael A. Eissenstat -- $t Proteases of the Hepatitis C virus / $r Andrea Urbani, Raffaele De Francesco, Christian Steink�uhler -- $t Human herpesvirus proteases / $r Xiayang Qiu, Sherin S. Abdel-Meguid -- $t Secreted proteinases from Candida : challenges for structure-aided drug design / $r Kent Stewart, Robert C. Goldman, Cele Abad-Zapatero -- $t Proteolytic enzymes of the viruses of the family picornaviridae / $r Ernest M. Bergmann, Michael N.G. James -- $t Proteases as drug targets for the treatment of malaria / $r Colin Berry -- $t Chagas disease / $r Juan Jos�e Cazzulo -- $t Cellular proteinases and viral infection : Influenza virus, Sendai virus, and HIV-1 / $r Hiroshi Kido ... [et al.] -- $t Bacterial type I signal peptidases / $r Mark O. Lively -- $t Proteinases involved in plant virus genome expression / $r Juan Antonio Garc�ia, Mar�ia Rosario Fern�andez-Fern�andez, Juan Jos�e L�opez-Moya.
520 $a Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery.
588 $a Description based on print version record.
650 0 $a Microbial enzymes. $3 280911
650 1 2 $a Protease Inhibitors $x chemical synthesis. $3 571433
650 1 2 $a Protease Inhibitors $x therapeutic use. $3 301252
650 2 2 $a Communicable Diseases $x enzymology. $3 571434
650 2 2 $a Communicable Diseases $x therapy. $3 571435
650 4 $a Communicable diseases. $3 265362
650 6 $a Enzymes prot�eolytiques. $3 571436
650 6 $a Antiprot�eases. $3 571437
650 6 $a Enzymes microbiennes. $3 571438
650 0 $a Proteolytic enzymes. $3 193678
650 0 $a Protease inhibitors. $3 250721
655 4 $a Electronic books. $2 local. $3 214472
700 1 $a Dunn, Ben M. $3 571432
776 0 8 $i Print version: $t Proteases of infectious agents. $d San Diego, Calif. : Academic, c1999 $z 0124205100 $z 9780124205109 $w (DLC) 98089642 $w (OCoLC)41072679
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780124205109
938 $a Ingram Digital eBook Collection $b IDEB $n 102511