語系:
繁體中文
English
說明(常見問題)
圖資館首頁
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
The quantal theory of immunitythe mo...
~
Smith, Kendall A.
The quantal theory of immunitythe molecular basis of autoimmunity and leukemia /
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
The quantal theory of immunityKendall A. Smith.
其他題名:
the molecular basis of autoimmunity and leukemia /
作者:
Smith, Kendall A.
出版者:
Singapore ;World Scientific Pub. Co.,c2010.
面頁冊數:
xi, 235 p. :ill. (some col.)
標題:
Immune response.
電子資源:
http://www.worldscientific.com/worldscibooks/10.1142/7269#t=toc
ISBN:
9789814271769 (electronic bk.)
The quantal theory of immunitythe molecular basis of autoimmunity and leukemia /
Smith, Kendall A.
The quantal theory of immunity
the molecular basis of autoimmunity and leukemia /[electronic resource] :Kendall A. Smith. - Singapore ;World Scientific Pub. Co.,c2010. - xi, 235 p. :ill. (some col.)
Includes bibliographical references and index.
This book explains how the immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none (quantal) manner. To date, there has not been a complete description of the immune system and its cells and molecules, primarily because most of the information has accumulated only in the last 40 years and our understanding has been expanding rapidly only in the last 20 years. It is now clear that the cells have evolved a way to "count" the number of foreign antigenic molecular "hits", and they only react when a critical number of events have accumulated. Subsequently, control over the reaction is transferred to a systemic lymphocytotrophic hormone system that determines the tempo, magnitude and duration of the immune reaction. This book explains in detail how the immune system, cells and molecules work for the first time. With this understanding as a basis, the pathogenesis of autoimmunity can now be understood as a mutational usurpation of the genes encoding molecules that participate in a sensitive feedback regulatory control of the immune reaction. By comparison, malignant transformation is understood as a mutational usurpation of the genes encoding the molecules that control the quantal decision to proliferate, so that normal ligand/receptor cell growth control is circumvented.
Electronic reproduction.
Singapore :
World Scientific Publishing Co.,
2010.
System requirements: Adobe Acrobat Reader.
ISBN: 9789814271769 (electronic bk.)Subjects--Topical Terms:
216499
Immune response.
LC Class. No.: QR186
Dewey Class. No.: 616.97/8
The quantal theory of immunitythe molecular basis of autoimmunity and leukemia /
LDR
:02552nmm a2200265 a 4500
001
345748
003
WSP
005
20101229102409.0
006
m d
007
cr cuu|||uu|||
008
121106s2010 si a sb 001 0 eng d
020
$a
9789814271769 (electronic bk.)
020
$z
9789814271752 (hbk.)
020
$z
9814271756 (hbk.)
035
$a
00001125
050
4
$a
QR186
082
0 4
$a
616.97/8
$2
22
100
1
$a
Smith, Kendall A.
$3
575848
245
1 4
$a
The quantal theory of immunity
$h
[electronic resource] :
$b
the molecular basis of autoimmunity and leukemia /
$c
Kendall A. Smith.
260
$a
Singapore ;
$a
Hackensack, N.J. :
$b
World Scientific Pub. Co.,
$c
c2010.
300
$a
xi, 235 p. :
$b
ill. (some col.)
504
$a
Includes bibliographical references and index.
520
$a
This book explains how the immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none (quantal) manner. To date, there has not been a complete description of the immune system and its cells and molecules, primarily because most of the information has accumulated only in the last 40 years and our understanding has been expanding rapidly only in the last 20 years. It is now clear that the cells have evolved a way to "count" the number of foreign antigenic molecular "hits", and they only react when a critical number of events have accumulated. Subsequently, control over the reaction is transferred to a systemic lymphocytotrophic hormone system that determines the tempo, magnitude and duration of the immune reaction. This book explains in detail how the immune system, cells and molecules work for the first time. With this understanding as a basis, the pathogenesis of autoimmunity can now be understood as a mutational usurpation of the genes encoding molecules that participate in a sensitive feedback regulatory control of the immune reaction. By comparison, malignant transformation is understood as a mutational usurpation of the genes encoding the molecules that control the quantal decision to proliferate, so that normal ligand/receptor cell growth control is circumvented.
533
$a
Electronic reproduction.
$b
Singapore :
$c
World Scientific Publishing Co.,
$d
2010.
$n
System requirements: Adobe Acrobat Reader.
$n
Mode of access: World Wide Web.
$n
Available to subscribing institutions.
650
0
$a
Immune response.
$3
216499
650
0
$a
Interleukin-2.
$3
575849
650
0
$a
T cells.
$3
224601
710
2
$a
World Scientific (Firm)
$3
575130
776
1
$z
9789814271752 (hbk.)
776
1
$z
9814271756 (hbk.)
856
4 0
$u
http://www.worldscientific.com/worldscibooks/10.1142/7269#t=toc
筆 0 讀者評論
全部
電子館藏
館藏
1 筆 • 頁數 1 •
1
條碼號
館藏地
館藏流通類別
資料類型
索書號
使用類型
借閱狀態
預約狀態
備註欄
附件
000000074996
電子館藏
1圖書
電子書
EB QR186 c2010
一般使用(Normal)
在架
0
1 筆 • 頁數 1 •
1
多媒體
多媒體檔案
http://www.worldscientific.com/worldscibooks/10.1142/7269#t=toc
評論
新增評論
分享你的心得
Export
取書館別
處理中
...
變更密碼
登入