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The MIF handbook
~
Bucala, Richard.
The MIF handbook
Record Type:
Electronic resources : Monograph/item
Title/Author:
The MIF handbookedited by Richard Bucala.
other author:
Bucala, Richard.
Published:
Singapore ;World Scientific,c2012.
Description:
1 online resource (viii, 390 p.) :ill.
Subject:
Cytokines.
Online resource:
http://www.worldscientific.com/worldscibooks/10.1142/8032#t=toc
ISBN:
9789814335362 (electronic bk.)
The MIF handbook
The MIF handbook
[electronic resource] /edited by Richard Bucala. - Singapore ;World Scientific,c2012. - 1 online resource (viii, 390 p.) :ill.
Includes bibliographical references and index.
The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.
ISBN: 9789814335362 (electronic bk.)Subjects--Topical Terms:
195178
Cytokines.
Index Terms--Genre/Form:
214472
Electronic books.
LC Class. No.: QP552.M54 / .M54 2012eb
Dewey Class. No.: 572/.696
The MIF handbook
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[electronic resource] /
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edited by Richard Bucala.
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Singapore ;
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Hackensack, NJ. :
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World Scientific,
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c2012.
300
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1 online resource (viii, 390 p.) :
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ill.
504
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Includes bibliographical references and index.
520
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The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.
588
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Description based on print version record.
650
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Cytokines.
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195178
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Immune response
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Regulation.
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Electronic books.
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Bucala, Richard.
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http://www.worldscientific.com/worldscibooks/10.1142/8032#t=toc
based on 0 review(s)
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電子館藏
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1 records • Pages 1 •
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000000093110
電子館藏
1圖書
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EB QP552.M54 2012eb
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1 records • Pages 1 •
1
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http://www.worldscientific.com/worldscibooks/10.1142/8032#t=toc
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