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Protein folding and metal ionsmechan...

Gomes, Cláudio M., (1970-)

Protein folding and metal ionsmechanisms, biology and disease /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Protein folding and metal ionsedited by Cláudio M. Gomes, Pernilla Wittung-Stafshede.
其他題名:	mechanisms, biology and disease /
其他作者:	Gomes, Cláudio M.,
出版者:	Boca Raton, FL :CRC Press,c2011.
面頁冊數:	1 online resource (xiv, 294 p.) :ill.
標題:	Metalloproteins.
電子資源:	http://www.crcnetbase.com/doi/book/10.1201/b10278
ISBN:	9781439809655 (electronic bk.)

Protein folding and metal ionsmechanisms, biology and disease /
Protein folding and metal ionsmechanisms, biology and disease /[electronic resource] :edited by Cláudio M. Gomes, Pernilla Wittung-Stafshede. - Boca Raton, FL :CRC Press,c2011. - 1 online resource (xiv, 294 p.) :ill.

Includes bibliographical references and index.

Cover13; -- Contents -- Preface -- Acknowledgments -- About the Editors -- Contributors -- Section I: Folding and Stability of Metalloproteins -- Chapter 1: Metal Ions, Protein Folding, and Conformational States -- Chapter 2: The Folding Mechanism of c-Type Cytochromes -- Chapter 3: The Mechanism of Cytochrome c Folding -- Chapter 4: Stability and Folding of Copper-Binding Proteins -- Chapter 5: Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability -- Chapter 6: Folding and Stability of Myoglobins and Hemoglobins -- Section II: Mechanisms of Metal Transporters and Assembly -- Chapter 7: Frataxin -- Chapter 8: Mechanism of Human Copper Transporter Wilsons Disease Protein -- Section III: Metal Ions, Protein Conformation, and Disease -- Chapter 9: 945;-Synuclein and Metals -- Chapter 10: Zinc and p53 Misfolding -- Chapter 11: The Octarepeat Domainof the Prion Protein andIts Role in Metal Ion Coordination and Disease -- Section IV: Metalloprotein Design, Simulation, and Models -- Chapter 12: Metallopeptides asTools to UnderstandMetalloprotein Folding and Stability -- Chapter 13: The Folding Landscapes of Metalloproteins -- Appendix -- Back cover.

"Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher.

ISBN: 9781439809655 (electronic bk.)

Standard No.: 9786612902710Subjects--Topical Terms:

194797
Metalloproteins.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: QP552.M46 / P765 2011eb

Dewey Class. No.: 572/.633

National Library of Medicine Call No.: QU 55.8

Protein folding and metal ionsmechanisms, biology and disease /
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035 $a (OCoLC)694271098 $z (OCoLC)741250045 $z (OCoLC)816619620
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245 0 0 $a Protein folding and metal ions $h [electronic resource] : $b mechanisms, biology and disease / $c edited by Cláudio M. Gomes, Pernilla Wittung-Stafshede.
260 $a Boca Raton, FL : $b CRC Press, $c c2011.
300 $a 1 online resource (xiv, 294 p.) : $b ill.
504 $a Includes bibliographical references and index.
505 0 $a Cover13; -- Contents -- Preface -- Acknowledgments -- About the Editors -- Contributors -- Section I: Folding and Stability of Metalloproteins -- Chapter 1: Metal Ions, Protein Folding, and Conformational States -- Chapter 2: The Folding Mechanism of c-Type Cytochromes -- Chapter 3: The Mechanism of Cytochrome c Folding -- Chapter 4: Stability and Folding of Copper-Binding Proteins -- Chapter 5: Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability -- Chapter 6: Folding and Stability of Myoglobins and Hemoglobins -- Section II: Mechanisms of Metal Transporters and Assembly -- Chapter 7: Frataxin -- Chapter 8: Mechanism of Human Copper Transporter Wilsons Disease Protein -- Section III: Metal Ions, Protein Conformation, and Disease -- Chapter 9: 945;-Synuclein and Metals -- Chapter 10: Zinc and p53 Misfolding -- Chapter 11: The Octarepeat Domainof the Prion Protein andIts Role in Metal Ion Coordination and Disease -- Section IV: Metalloprotein Design, Simulation, and Models -- Chapter 12: Metallopeptides asTools to UnderstandMetalloprotein Folding and Stability -- Chapter 13: The Folding Landscapes of Metalloproteins -- Appendix -- Back cover.
520 $a "Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher.
588 0 $a Print version record.
650 0 $a Metalloproteins. $3 194797
650 0 $a Protein folding. $3 192285
650 2 2 $a Metallochaperones. $3 696879
650 2 2 $a Protein Conformation. $3 225219
650 2 2 $a Protein Folding. $3 303195
650 2 2 $a Protein Stability. $3 696880
655 0 $a Electronic books. $2 local. $3 214472
700 1 $a Gomes, Cláudio M., $d 1970- $3 696877
700 1 $a Wittung-Stafshede, Pernilla, $d 1968- $3 696878
856 4 0 $u http://www.crcnetbase.com/doi/book/10.1201/b10278