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Bioisosteres in medicinal chemistry

Brown, Nathan.

Bioisosteres in medicinal chemistry

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Bioisosteres in medicinal chemistryedited by Nathan Brown.
其他作者:	Brown, Nathan.
出版者:	Hoboken :John Wiley & Sons,2012.
面頁冊數:	1 online resource.
標題:	DrugsDesign.
電子資源:	http://onlinelibrary.wiley.com/book/10.1002/9783527654307
ISBN:	9783527654307 (electronic bk.)

Bioisosteres in medicinal chemistry
Bioisosteres in medicinal chemistry[electronic resource] /edited by Nathan Brown. - Hoboken :John Wiley & Sons,2012. - 1 online resource. - Methods and principles in medicinal chemistry ;v. 54. - Methods and principles in medicinal chemistry ;v. 39..

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologi.

ISBN: 9783527654307 (electronic bk.)Subjects--Topical Terms:

201742
Drugs
--Design.

LC Class. No.: RS420

Dewey Class. No.: 615.19

Bioisosteres in medicinal chemistry
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520 $a Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologi.
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