國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Control and prediction of solid-stat...

Bhardwaj, Rajni Miglani.

Control and prediction of solid-state of pharmaceuticalsexperimental and computational approaches /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Control and prediction of solid-state of pharmaceuticalsby Rajni Miglani Bhardwaj.
其他題名:	experimental and computational approaches /
作者:	Bhardwaj, Rajni Miglani.
出版者:	Cham :Springer International Publishing :2016.
面頁冊數:	xxxvii, 238 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Pharmaceutical chemistry.
電子資源:	http://dx.doi.org/10.1007/978-3-319-27555-0
ISBN:	9783319275550$q(electronic bk.)

Control and prediction of solid-state of pharmaceuticalsexperimental and computational approaches /
Bhardwaj, Rajni Miglani.

Control and prediction of solid-state of pharmaceuticalsexperimental and computational approaches /[electronic resource] :by Rajni Miglani Bhardwaj. - Cham :Springer International Publishing :2016. - xxxvii, 238 p. :ill., digital ;24 cm. - Springer theses,2190-5053. - Springer theses..

This thesis investigates a range of experimental and computational approaches to the discovery of solid forms. It illustrates an inexpensive, practical and accurate way to predict the crystallizability of organic compounds based on molecular structure alone, while also highlighting the molecular factors that inhibit or promote crystallization. Furthermore, readers will gain a better understanding of the key factors underpinning solid-state structure and diversity. A major part of the thesis highlights experimental work carried out on two structurally very similar compounds, while another main section examines the influence of small changes in structure and substituents on solid-state structure and diversity using computational tools including crystal structure prediction, PIXEL calculations, Xpac, Mercury and statistical modelling tools. In closing, the author presents a fast validated method for solid-state form screening using Raman microscopy on multi-well plates to explore the experimental crystallization space.

ISBN: 9783319275550$q(electronic bk.)

Standard No.: 10.1007/978-3-319-27555-0doiSubjects--Topical Terms:

203135
Pharmaceutical chemistry.

LC Class. No.: RS420

Dewey Class. No.: 615.19

Control and prediction of solid-state of pharmaceuticalsexperimental and computational approaches /
LDR:02052nmm a2200313 a 4500 001 483187
003 DE-He213
005 20160824094329.0
006 m d
007 cr nn 008maaau
008 161007s2016 gw s 0 eng d
020 $a 9783319275550$q(electronic bk.)
020 $a 9783319275543$q(paper)
024 7 $a 10.1007/978-3-319-27555-0 $2 doi
035 $a 978-3-319-27555-0
040 $a GP $c GP
041 0 $a eng
050 4 $a RS420
072 7 $a PNR $2 bicssc
072 7 $a SCI013050 $2 bisacsh
082 0 4 $a 615.19 $2 23
090 $a RS420 $b .B575 2016
100 1 $a Bhardwaj, Rajni Miglani. $3 740593
245 1 0 $a Control and prediction of solid-state of pharmaceuticals $h [electronic resource] : $b experimental and computational approaches / $c by Rajni Miglani Bhardwaj.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a xxxvii, 238 p. : $b ill., digital ; $c 24 cm.
490 1 $a Springer theses, $x 2190-5053
520 $a This thesis investigates a range of experimental and computational approaches to the discovery of solid forms. It illustrates an inexpensive, practical and accurate way to predict the crystallizability of organic compounds based on molecular structure alone, while also highlighting the molecular factors that inhibit or promote crystallization. Furthermore, readers will gain a better understanding of the key factors underpinning solid-state structure and diversity. A major part of the thesis highlights experimental work carried out on two structurally very similar compounds, while another main section examines the influence of small changes in structure and substituents on solid-state structure and diversity using computational tools including crystal structure prediction, PIXEL calculations, Xpac, Mercury and statistical modelling tools. In closing, the author presents a fast validated method for solid-state form screening using Raman microscopy on multi-well plates to explore the experimental crystallization space.
650 0 $a Pharmaceutical chemistry. $3 203135
650 0 $a Solid dosage forms. $3 302713
650 0 $a Drugs $x Design. $3 201742
650 1 4 $a Chemistry. $3 188628
650 2 4 $a Physical Chemistry. $3 273698
650 2 4 $a Pharmaceutical Sciences/Technology. $3 338426
650 2 4 $a Theoretical and Computational Chemistry. $3 273882
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a Springer theses. $3 557607
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-27555-0
950 $a Chemistry and Materials Science (Springer-11644)