語系:
繁體中文
English
說明(常見問題)
圖資館首頁
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
Protein targeting compoundspredictio...
~
Boldicke, Thomas.
Protein targeting compoundsprediction, selection and activity of specific inhibitors /
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Protein targeting compoundsedited by Thomas Boldicke.
其他題名:
prediction, selection and activity of specific inhibitors /
其他作者:
Boldicke, Thomas.
出版者:
Cham :Springer International Publishing :2016.
面頁冊數:
viii, 288 p. :ill., digital ;24 cm.
Contained By:
Springer eBooks
標題:
ProteinsSynthesis
電子資源:
http://dx.doi.org/10.1007/978-3-319-32805-8
ISBN:
9783319328058$q(electronic bk.)
Protein targeting compoundsprediction, selection and activity of specific inhibitors /
Protein targeting compounds
prediction, selection and activity of specific inhibitors /[electronic resource] :edited by Thomas Boldicke. - Cham :Springer International Publishing :2016. - viii, 288 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.9170065-2598 ;. - Advances in experimental medicine and biology ;946..
Introduction -- Part I Methods of Structure Prediction -- Chapter 1 In Silico Prediction of Target-Inhibitor Interactions -- Part II Antibodies -- Chapter 2 Antibodies and Selection of Monoclonal Antibodies -- Chapter 3 Selection of Recombinant Human Antibodies -- Chapter 4 Selection of Recombinant Human Antibodies against Toxins and Viruses -- Chapter 5 Recent Advances with ER Targeted Intrabodies -- Chapter 6 Therapeutic Blocking Antibodies against Oncogenic Receptors and Growth Factors -- Chapter 7 Synthetic Cystine-Knot Miniproteins-Valuable Scaffolds for Polypeptide Engineering -- Part III Peptides, Small Molecules and Aptamers -- Chapter 8 Peptides and Peptide Analogs to Inhibit Protein -- Chapter 9 Allosteric Modulators of the Class A G Protein coupled Receptors -- Chapter 10 Phosphatases: Their Roles in Cancer and their Chemical Modulators -- Chapter 11 Selection and Application of Aptamers and Intramers -- Part IV Angiogenesis Inhibitors -- Chapter 12 Inhibitors of Angiogenesis.
This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the in silico prediction of target-inhibitor interactions. Key aspects of this book are: - Selection strategies for monoclonal and recombinant human antibodies - Selection strategies for ER intrabodies, peptides and aptamers - Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology - Antibodies for cancer therapy and inhibitors of angiogenesis. The book will be of great interest to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions.
ISBN: 9783319328058$q(electronic bk.)
Standard No.: 10.1007/978-3-319-32805-8doiSubjects--Topical Terms:
566809
Proteins
--Synthesis
LC Class. No.: QP551
Dewey Class. No.: 572.645
Protein targeting compoundsprediction, selection and activity of specific inhibitors /
LDR
:03352nmm a2200325 a 4500
001
489000
003
DE-He213
005
20161019141050.0
006
m d
007
cr nn 008maaau
008
161213s2016 gw s 0 eng d
020
$a
9783319328058$q(electronic bk.)
020
$a
9783319328041$q(paper)
024
7
$a
10.1007/978-3-319-32805-8
$2
doi
035
$a
978-3-319-32805-8
040
$a
GP
$c
GP
041
0
$a
eng
050
4
$a
QP551
072
7
$a
MJCM
$2
bicssc
072
7
$a
MED044000
$2
bisacsh
082
0 4
$a
572.645
$2
23
090
$a
QP551
$b
.P967 2016
245
0 0
$a
Protein targeting compounds
$h
[electronic resource] :
$b
prediction, selection and activity of specific inhibitors /
$c
edited by Thomas Boldicke.
260
$a
Cham :
$b
Springer International Publishing :
$b
Imprint: Springer,
$c
2016.
300
$a
viii, 288 p. :
$b
ill., digital ;
$c
24 cm.
490
1
$a
Advances in experimental medicine and biology,
$x
0065-2598 ;
$v
v.917
505
0
$a
Introduction -- Part I Methods of Structure Prediction -- Chapter 1 In Silico Prediction of Target-Inhibitor Interactions -- Part II Antibodies -- Chapter 2 Antibodies and Selection of Monoclonal Antibodies -- Chapter 3 Selection of Recombinant Human Antibodies -- Chapter 4 Selection of Recombinant Human Antibodies against Toxins and Viruses -- Chapter 5 Recent Advances with ER Targeted Intrabodies -- Chapter 6 Therapeutic Blocking Antibodies against Oncogenic Receptors and Growth Factors -- Chapter 7 Synthetic Cystine-Knot Miniproteins-Valuable Scaffolds for Polypeptide Engineering -- Part III Peptides, Small Molecules and Aptamers -- Chapter 8 Peptides and Peptide Analogs to Inhibit Protein -- Chapter 9 Allosteric Modulators of the Class A G Protein coupled Receptors -- Chapter 10 Phosphatases: Their Roles in Cancer and their Chemical Modulators -- Chapter 11 Selection and Application of Aptamers and Intramers -- Part IV Angiogenesis Inhibitors -- Chapter 12 Inhibitors of Angiogenesis.
520
$a
This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the in silico prediction of target-inhibitor interactions. Key aspects of this book are: - Selection strategies for monoclonal and recombinant human antibodies - Selection strategies for ER intrabodies, peptides and aptamers - Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology - Antibodies for cancer therapy and inhibitors of angiogenesis. The book will be of great interest to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions.
650
0
$a
Proteins
$x
Synthesis
$x
Inhibitors.
$3
566809
650
1 4
$a
Biomedicine.
$3
273648
650
2 4
$a
Immunology.
$3
189152
700
1
$a
Boldicke, Thomas.
$3
747207
710
2
$a
SpringerLink (Online service)
$3
273601
773
0
$t
Springer eBooks
830
0
$a
Advances in experimental medicine and biology ;
$v
946.
$3
557559
856
4 0
$u
http://dx.doi.org/10.1007/978-3-319-32805-8
950
$a
Biomedical and Life Sciences (Springer-11642)
筆 0 讀者評論
全部
電子館藏
館藏
1 筆 • 頁數 1 •
1
條碼號
館藏地
館藏流通類別
資料類型
索書號
使用類型
借閱狀態
預約狀態
備註欄
附件
000000126511
電子館藏
1圖書
電子書
EB QP551 P967 2016
一般使用(Normal)
在架
0
1 筆 • 頁數 1 •
1
多媒體
多媒體檔案
http://dx.doi.org/10.1007/978-3-319-32805-8
評論
新增評論
分享你的心得
Export
取書館別
處理中
...
變更密碼
登入