國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Inflammation and metastasis

Maru, Yoshiro.

Inflammation and metastasis

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Inflammation and metastasisby Yoshiro Maru.
作者:	Maru, Yoshiro.
出版者:	Tokyo :Springer Japan :2016.
面頁冊數:	xx, 505 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Inflammation.
電子資源:	http://dx.doi.org/10.1007/978-4-431-56024-1
ISBN:	9784431560241$q(electronic bk.)

Inflammation and metastasis
Maru, Yoshiro.

Inflammation and metastasis[electronic resource] /by Yoshiro Maru. - Tokyo :Springer Japan :2016. - xx, 505 p. :ill., digital ;24 cm.

This book provides the latest information on cancer metastasis from the standpoint of inflammation, especially innate immune reactions caused by endogenous mediators but not exogenous pathogens, with ideas on how to understand the complicated mechanisms of metastasis as well as to interpret therapeutic targets. The book includes the topic of the emerging roles of endogenous TLR4 ligands whose functions are shared intriguingly by metastasis and auto-inflammatory diseases such as rheumatoid arthritis. For example, most cancer therapies established so far are effective initially. However, they eventually face the great obstacles of drug resistance, immune evasion, and metastatic progression. One of the endogenous TLR4 ligands is thought to contribute to all three processes. The most important features of the book are to explain a concept of homeostatic inflammation, disturbance of which in the lungs gives rise to the establishment of a pre-metastatic pulmonary microenvironment based on primary tumor-mediated hijacking of the innate immune defense system against respiratory infection. In addition, structure-based thinking is another important feature of this book. It is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, in the center of which cancer is located. Given the proposal of precision medicine by President Obama in the United States in 2015 and the recent success of immune-modulator-based therapy, this book will appeal to researchers in a variety of fields with the title of the book connecting the worst disease (metastasis) and the most fundamental event (inflammation) that is common to many diseases.

ISBN: 9784431560241$q(electronic bk.)

Standard No.: 10.1007/978-4-431-56024-1doiSubjects--Topical Terms:

250775
Inflammation.

LC Class. No.: RB131

Dewey Class. No.: 616.0473

Inflammation and metastasis
LDR:02561nmm a2200301 a 4500 001 492702
003 DE-He213
005 20161213102520.0
006 m d
007 cr nn 008maaau
008 170220s2016 ja s 0 eng d
020 $a 9784431560241$q(electronic bk.)
020 $a 9784431560227$q(paper)
024 7 $a 10.1007/978-4-431-56024-1 $2 doi
035 $a 978-4-431-56024-1
040 $a GP $c GP
041 0 $a eng
050 4 $a RB131
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
082 0 4 $a 616.0473 $2 23
090 $a RB131 $b .M389 2016
100 1 $a Maru, Yoshiro. $3 753079
245 1 0 $a Inflammation and metastasis $h [electronic resource] / $c by Yoshiro Maru.
260 $a Tokyo : $b Springer Japan : $b Imprint: Springer, $c 2016.
300 $a xx, 505 p. : $b ill., digital ; $c 24 cm.
520 $a This book provides the latest information on cancer metastasis from the standpoint of inflammation, especially innate immune reactions caused by endogenous mediators but not exogenous pathogens, with ideas on how to understand the complicated mechanisms of metastasis as well as to interpret therapeutic targets. The book includes the topic of the emerging roles of endogenous TLR4 ligands whose functions are shared intriguingly by metastasis and auto-inflammatory diseases such as rheumatoid arthritis. For example, most cancer therapies established so far are effective initially. However, they eventually face the great obstacles of drug resistance, immune evasion, and metastatic progression. One of the endogenous TLR4 ligands is thought to contribute to all three processes. The most important features of the book are to explain a concept of homeostatic inflammation, disturbance of which in the lungs gives rise to the establishment of a pre-metastatic pulmonary microenvironment based on primary tumor-mediated hijacking of the innate immune defense system against respiratory infection. In addition, structure-based thinking is another important feature of this book. It is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, in the center of which cancer is located. Given the proposal of precision medicine by President Obama in the United States in 2015 and the recent success of immune-modulator-based therapy, this book will appeal to researchers in a variety of fields with the title of the book connecting the worst disease (metastasis) and the most fundamental event (inflammation) that is common to many diseases.
650 0 $a Inflammation. $3 250775
650 0 $a Metastasis. $3 345769
650 0 $a Cancer $x Molecular aspects. $3 221221
650 0 $a Cancer $x Immunological aspects. $3 484440
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Cancer Research. $3 273660
650 2 4 $a Human Physiology. $3 274509
650 2 4 $a Immunology. $3 189152
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-4-431-56024-1
950 $a Biomedical and Life Sciences (Springer-11642)