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Endothelial progenitor cellsa new re...

Balistreri, Carmela Rita.

Endothelial progenitor cellsa new real hope? /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Endothelial progenitor cellsby Carmela Rita Balistreri.
其他題名:	a new real hope? /
作者:	Balistreri, Carmela Rita.
出版者:	Cham :Springer International Publishing :2017.
面頁冊數:	xxii, 80 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Stem cells.
電子資源:	http://dx.doi.org/10.1007/978-3-319-55107-4
ISBN:	9783319551074$q(electronic bk.)

Endothelial progenitor cellsa new real hope? /
Balistreri, Carmela Rita.

Endothelial progenitor cellsa new real hope? /[electronic resource] :by Carmela Rita Balistreri. - Cham :Springer International Publishing :2017. - xxii, 80 p. :ill., digital ;24 cm. - UNIPA Springer series,2366-7516. - UNIPA Springer series..

Preface -- From the Regenerative Medicine to Endothelial progenitor cells as potential candidates -- Endothelial progenitor cells and their clinical applications as potential disease biomarkers and therapeutic agents: evidence and controversies in their effectiveness -- EPCs: a real hope or an unrealizable dream? Which measures or strategies are necessary for achieving the real hope? Focus on a potential roadmap.

This book explores the role of endothelial progenitor cells (EPCs) in the context of regenerative medicine (RegMed) In particular, it reveals the value of RegMed as a new TM branch intended to improve the health and quality of life, by restoring, maintaining or enhancing tissue and functions of organs. The book is divided into three chapters, the first of which describes the relevance of translational medicine (TM) as a new research approach to counteract the imposing challengeof age-related diseases. Of the diverse RegMed approaches, particular attention is paid to stem/progenitor cell-based therapies, their benefits and shortcomings, as well as to the description of types of stem and progenitor cells considered for regenerative cell therapies, such as EPCs as emerging candidates for RegMed applications. In turn, the second chapter outlines the clinical relevance of EPCs as both potential predictors, diagnostic and prognostic biomarkers of age-related diseases and therapeutic agents,discussing their advantages, disadvantages, and conflicting data. Chapter three proposes a potential roadmap for revising the findings and creating a clearer picture of valid data, which can provide support for various important aspects, i.e.isolating and characterizing EPCs by establishing standardized criteria for EPC research, identifying appropriate sub-populations for cell therapy, timing, dosing, priming of cells,and defining delivery modes for different applications. The book concludes with an overview of innovative strategies that could improve the efficacy of cell therapy at all levels, including cell priming, bio-nanotechnology, and tissue engineering.

ISBN: 9783319551074$q(electronic bk.)

Standard No.: 10.1007/978-3-319-55107-4doiSubjects--Topical Terms:

200260
Stem cells.

LC Class. No.: QH588.S83

Dewey Class. No.: 616.02774

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520 $a This book explores the role of endothelial progenitor cells (EPCs) in the context of regenerative medicine (RegMed) In particular, it reveals the value of RegMed as a new TM branch intended to improve the health and quality of life, by restoring, maintaining or enhancing tissue and functions of organs. The book is divided into three chapters, the first of which describes the relevance of translational medicine (TM) as a new research approach to counteract the imposing challengeof age-related diseases. Of the diverse RegMed approaches, particular attention is paid to stem/progenitor cell-based therapies, their benefits and shortcomings, as well as to the description of types of stem and progenitor cells considered for regenerative cell therapies, such as EPCs as emerging candidates for RegMed applications. In turn, the second chapter outlines the clinical relevance of EPCs as both potential predictors, diagnostic and prognostic biomarkers of age-related diseases and therapeutic agents,discussing their advantages, disadvantages, and conflicting data. Chapter three proposes a potential roadmap for revising the findings and creating a clearer picture of valid data, which can provide support for various important aspects, i.e.isolating and characterizing EPCs by establishing standardized criteria for EPC research, identifying appropriate sub-populations for cell therapy, timing, dosing, priming of cells,and defining delivery modes for different applications. The book concludes with an overview of innovative strategies that could improve the efficacy of cell therapy at all levels, including cell priming, bio-nanotechnology, and tissue engineering.
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