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Extracellular matrix in tumor biology

Brekken, Rolf A.

Extracellular matrix in tumor biology

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Extracellular matrix in tumor biologyedited by Rolf A. Brekken, Dwayne Stupack.
其他作者:	Brekken, Rolf A.
出版者:	Cham :Springer International Publishing :2017.
面頁冊數:	ix, 115 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Extracellular matrix.
電子資源:	http://dx.doi.org/10.1007/978-3-319-60907-2
ISBN:	9783319609072$q(electronic bk.)

Extracellular matrix in tumor biology
Extracellular matrix in tumor biology[electronic resource] /edited by Rolf A. Brekken, Dwayne Stupack. - Cham :Springer International Publishing :2017. - ix, 115 p. :ill., digital ;24 cm. - Biology of extracellular matrix,0887-3224. - Biology of extracellular matrix..

1. The extracellular matrix of tumors: a focus on fibronectin and fibulin-5 -- 2. Internalization of collagen: an important matrix turnover pathway in cancer -- 3. Lumican, a Small Leucine-Rich Proteoglycan, and Its Biological Function in Tumor Progression -- 4. Versican: Role in Cancer Tumorigenesis -- 5. Engineering advanced models of the glioblastoma microenvironment using biomaterials -- 6. Breaching and opening basement membrane barriers: the anchor cell leads the way.

This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression. The book addresses researchers working on cancer biology or ECM, and oncologists alike.

ISBN: 9783319609072$q(electronic bk.)

Standard No.: 10.1007/978-3-319-60907-2doiSubjects--Topical Terms:

195330
Extracellular matrix.

LC Class. No.: QH603.E93

Dewey Class. No.: 572.6

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520 $a This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression. The book addresses researchers working on cancer biology or ECM, and oncologists alike.
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