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Targeting protein-protein interactio...

Georg, Gunda I.

Targeting protein-protein interactions by small molecules

Record Type:	Electronic resources : Monograph/item
Title/Author:	Targeting protein-protein interactions by small moleculesedited by Chunquan Sheng, Gunda I. Georg.
other author:	Sheng, Chunquan.
Published:	Singapore :Springer Singapore :2018.
Description:	xi, 329 p. :digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Protein-protein interactions.
Online resource:	http://dx.doi.org/10.1007/978-981-13-0773-7
ISBN:	9789811307737$q(electronic bk.)

Targeting protein-protein interactions by small molecules
Targeting protein-protein interactions by small molecules[electronic resource] /edited by Chunquan Sheng, Gunda I. Georg. - Singapore :Springer Singapore :2018. - xi, 329 p. :digital ;24 cm.

This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.

ISBN: 9789811307737$q(electronic bk.)

Standard No.: 10.1007/978-981-13-0773-7doiSubjects--Topical Terms:

265915
Protein-protein interactions.

LC Class. No.: QP551.5 / .T374 2018

Dewey Class. No.: 572.64

Targeting protein-protein interactions by small molecules
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245 0 0 $a Targeting protein-protein interactions by small molecules $h [electronic resource] / $c edited by Chunquan Sheng, Gunda I. Georg.
260 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2018.
300 $a xi, 329 p. : $b digital ; $c 24 cm.
520 $a This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.
650 0 $a Protein-protein interactions. $3 265915
650 0 $a Molecular association. $3 273472
650 0 $a Biochemistry. $3 188609
650 1 4 $a Chemistry. $3 188628
650 2 4 $a Medicinal Chemistry. $3 275183
650 2 4 $a Pharmaceutical Sciences/Technology. $3 338426
650 2 4 $a Bioorganic Chemistry. $3 275016
650 2 4 $a Protein Science. $3 376428
700 1 $a Sheng, Chunquan. $3 818702
700 1 $a Georg, Gunda I. $3 818703
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856 4 0 $u http://dx.doi.org/10.1007/978-981-13-0773-7
950 $a Chemistry and Materials Science (Springer-11644)