國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Total synthesis of indole alkaloidsb...

Matsuoka, Junpei.

Total synthesis of indole alkaloidsbased on direct construction of pyrrolocarbazole scaffolds via gold-catalyzed cascade cyclizations /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Total synthesis of indole alkaloidsby Junpei Matsuoka.
其他題名:	based on direct construction of pyrrolocarbazole scaffolds via gold-catalyzed cascade cyclizations /
作者:	Matsuoka, Junpei.
出版者:	Singapore :Springer Singapore :2020.
面頁冊數:	xii, 82 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Indole alkaloidsSynthesis.
電子資源:	https://doi.org/10.1007/978-981-15-8652-1
ISBN:	9789811586521$q(electronic bk.)

Total synthesis of indole alkaloidsbased on direct construction of pyrrolocarbazole scaffolds via gold-catalyzed cascade cyclizations /
Matsuoka, Junpei.

Total synthesis of indole alkaloidsbased on direct construction of pyrrolocarbazole scaffolds via gold-catalyzed cascade cyclizations /[electronic resource] :by Junpei Matsuoka. - Singapore :Springer Singapore :2020. - xii, 82 p. :ill., digital ;24 cm. - Springer theses,2190-5053. - Springer theses..

1. Introduction -- 2. Total Synthesis of Dictyodendrin A-F by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles -- 3. Construction of the Pyrrolo[2,3-d]carbazole Core of Spiroindoline Alkaloids by Gold-Catalyzed Cascade Cyclization of Ynamide.

This book explores efficient syntheses of indole alkaloids based on gold-catalyzed cascade cyclizations, presenting two strategies for total synthesis of these natural products based on gold-catalyzed reactions of conjugated diyne or ynamide. The book first describes the total and formal synthesis of dictyodendrins A-F based on direct construction of the pyrrolo[2,3-c]carbazole core using the gold-catalyzed annulation of azido-diynes and protected pyrrole. This synthetic strategy features late-stage functionalization of the pyrrolo[2,3-c]carbazole scaffold at several positions and allows diverse access to dictyodendrins and their derivatives. Secondly, the book discusses the formal synthesis of vindorosine based on the pyrrolo[2,3-d]carbazole construction using the gold-catalyzed cascade cyclization of ynamide. Importantly, the reaction using a chiral gold complex provides the optically active pyrrolo[2,3-d]carbazole. This strategy facilitates the rapid construction of the pyrrolocarbazole core structure of aspidosperma and related alkaloids, including vindorosine. These methodologies can accelerate the medicinal application of pyrrolocarbazole-type alkaloids and related compounds.

ISBN: 9789811586521$q(electronic bk.)

Standard No.: 10.1007/978-981-15-8652-1doiSubjects--Topical Terms:

877128
Indole alkaloids
--Synthesis.

LC Class. No.: QP801.I45

Dewey Class. No.: 572.549

Total synthesis of indole alkaloidsbased on direct construction of pyrrolocarbazole scaffolds via gold-catalyzed cascade cyclizations /
LDR:02580nmm a2200337 a 4500 001 585863
003 DE-He213
005 20201231144331.0
006 m d
007 cr nn 008maaau
008 210323s2020 si s 0 eng d
020 $a 9789811586521$q(electronic bk.)
020 $a 9789811586514$q(paper)
024 7 $a 10.1007/978-981-15-8652-1 $2 doi
035 $a 978-981-15-8652-1
040 $a GP $c GP
041 0 $a eng
050 4 $a QP801.I45
072 7 $a PNN $2 bicssc
072 7 $a SCI013040 $2 bisacsh
072 7 $a PNN $2 thema
082 0 4 $a 572.549 $2 23
090 $a QP801.I45 $b M434 2020
100 1 $a Matsuoka, Junpei. $3 877127
245 1 0 $a Total synthesis of indole alkaloids $h [electronic resource] : $b based on direct construction of pyrrolocarbazole scaffolds via gold-catalyzed cascade cyclizations / $c by Junpei Matsuoka.
260 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2020.
300 $a xii, 82 p. : $b ill., digital ; $c 24 cm.
490 1 $a Springer theses, $x 2190-5053
505 0 $a 1. Introduction -- 2. Total Synthesis of Dictyodendrin A-F by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles -- 3. Construction of the Pyrrolo[2,3-d]carbazole Core of Spiroindoline Alkaloids by Gold-Catalyzed Cascade Cyclization of Ynamide.
520 $a This book explores efficient syntheses of indole alkaloids based on gold-catalyzed cascade cyclizations, presenting two strategies for total synthesis of these natural products based on gold-catalyzed reactions of conjugated diyne or ynamide. The book first describes the total and formal synthesis of dictyodendrins A-F based on direct construction of the pyrrolo[2,3-c]carbazole core using the gold-catalyzed annulation of azido-diynes and protected pyrrole. This synthetic strategy features late-stage functionalization of the pyrrolo[2,3-c]carbazole scaffold at several positions and allows diverse access to dictyodendrins and their derivatives. Secondly, the book discusses the formal synthesis of vindorosine based on the pyrrolo[2,3-d]carbazole construction using the gold-catalyzed cascade cyclization of ynamide. Importantly, the reaction using a chiral gold complex provides the optically active pyrrolo[2,3-d]carbazole. This strategy facilitates the rapid construction of the pyrrolocarbazole core structure of aspidosperma and related alkaloids, including vindorosine. These methodologies can accelerate the medicinal application of pyrrolocarbazole-type alkaloids and related compounds.
650 0 $a Indole alkaloids $x Synthesis. $3 877128
650 1 4 $a Organic Chemistry. $3 274120
650 2 4 $a Catalysis. $3 188259
650 2 4 $a Inorganic Chemistry. $3 273692
650 2 4 $a Chemistry/Food Science, general. $3 274166
650 2 4 $a Medicinal Chemistry. $3 275183
650 2 4 $a Pharmaceutical Sciences/Technology. $3 338426
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer Nature eBook
830 0 $a Springer theses. $3 557607
856 4 0 $u https://doi.org/10.1007/978-981-15-8652-1
950 $a Chemistry and Materials Science (SpringerNature-11644)