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Circadian pharmacokinetics

Dong, Dong.

Circadian pharmacokinetics

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Circadian pharmacokineticsedited by Baojian Wu, Danyi Lu, Dong Dong.
其他作者:	Wu, Baojian.
出版者:	Singapore :Springer Singapore :2020.
面頁冊數:	vii, 253 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Pharmacokinetics.
電子資源:	https://doi.org/10.1007/978-981-15-8807-5
ISBN:	9789811588075$q(electronic bk.)

Circadian pharmacokinetics
Circadian pharmacokinetics[electronic resource] /edited by Baojian Wu, Danyi Lu, Dong Dong. - Singapore :Springer Singapore :2020. - vii, 253 p. :ill. (some col.), digital ;24 cm.

Chapter 1. Introduction to mammalian circadian clock system -- Chapter 2. Introduction to pharmacokinetics -- Chapter 3. Circadian clock and metabolic diseases -- Chapter 4. Circadian clock and CYP metabolism -- Chapter 5. Circadian clock and non-CYP phase I metabolism -- Chapter 6. Circadian clock and phase II metabolism -- Chapter 7. Circadian clock and uptake transporters -- Chapter 8. Circadian clock and efflux transporters -- Chapter 9. Role of pharmacokinetics in chronotherapeutics -- Chapter 10. Role of non-pharmacokinetic factors in chronoefficacy.

This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.

ISBN: 9789811588075$q(electronic bk.)

Standard No.: 10.1007/978-981-15-8807-5doiSubjects--Topical Terms:

190329
Pharmacokinetics.

LC Class. No.: RM301.5 / .C57 2020

Dewey Class. No.: 615.7

Circadian pharmacokinetics
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505 0 $a Chapter 1. Introduction to mammalian circadian clock system -- Chapter 2. Introduction to pharmacokinetics -- Chapter 3. Circadian clock and metabolic diseases -- Chapter 4. Circadian clock and CYP metabolism -- Chapter 5. Circadian clock and non-CYP phase I metabolism -- Chapter 6. Circadian clock and phase II metabolism -- Chapter 7. Circadian clock and uptake transporters -- Chapter 8. Circadian clock and efflux transporters -- Chapter 9. Role of pharmacokinetics in chronotherapeutics -- Chapter 10. Role of non-pharmacokinetic factors in chronoefficacy.
520 $a This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.
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