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X-ray phase-contrast tomographyunder...

Brombal, Luca.

X-ray phase-contrast tomographyunderlying physics and developments for breast imaging /

Record Type:	Electronic resources : Monograph/item
Title/Author:	X-ray phase-contrast tomographyby Luca Brombal.
Reminder of title:	underlying physics and developments for breast imaging /
Author:	Brombal, Luca.
Published:	Cham :Springer International Publishing :2020.
Description:	xiii, 140 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	BreastCancer
Online resource:	https://doi.org/10.1007/978-3-030-60433-2
ISBN:	9783030604332$q(electronic bk.)

X-ray phase-contrast tomographyunderlying physics and developments for breast imaging /
Brombal, Luca.

X-ray phase-contrast tomographyunderlying physics and developments for breast imaging /[electronic resource] :by Luca Brombal. - Cham :Springer International Publishing :2020. - xiii, 140 p. :ill., digital ;24 cm. - Springer theses,2190-5053. - Springer theses..

Introduction -- Physics of Propagation-based X-ray Tomography -- Propagation-based Breast CT and SYRMA-3D Project -- Detector and Pre-processing -- Experimental Optimization of Propagation-based BCT -- Three-Dimensional Imaging: A Clinically Oriented Focus -- Do We Need Clinical Applications in Synchrotrons? -- Conclusions.

X-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with "real world" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals.

ISBN: 9783030604332$q(electronic bk.)

Standard No.: 10.1007/978-3-030-60433-2doiSubjects--Topical Terms:

881799
Breast
--Cancer

LC Class. No.: RC280.B8 / B76 2020

Dewey Class. No.: 616.99449

X-ray phase-contrast tomographyunderlying physics and developments for breast imaging /
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