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PET and SPECT of neurobiological systems
~
Dierckx, Rudi A. J. O.
PET and SPECT of neurobiological systems
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
PET and SPECT of neurobiological systemsedited by Rudi A. J. O. Dierckx .. [et al.].
其他作者:
Dierckx, Rudi A. J. O.
出版者:
Cham :Springer International Publishing :2021.
面頁冊數:
xii, 1132 p. :ill., digital ;24 cm.
Contained By:
Springer Nature eBook
標題:
Tomography, Emission.
電子資源:
https://doi.org/10.1007/978-3-030-53176-8
ISBN:
9783030531768$q(electronic bk.)
PET and SPECT of neurobiological systems
PET and SPECT of neurobiological systems
[electronic resource] /edited by Rudi A. J. O. Dierckx .. [et al.]. - Second edition. - Cham :Springer International Publishing :2021. - xii, 1132 p. :ill., digital ;24 cm.
PART I BASICS: Animal Models for Brain Research -- Small Animal Molecular Imaging - uPET, uSPECT -- Cerebral Glucose Metabolism -- Cerebral Blood Flow Measurement with 15O-Water PET -- Principles of Brain Perfusion SPECT -- The Impact of Genetic Polymorphisms on Neuroreceptor Imaging -- PART II SYSTEMS: Acetylcholinesterase -- Adenosine Receptors -- Beta-Amyloid and Other Proteinopathies -- Central Benzodiazepine Receptors -- Cyclooxygenase-2 -- Dopamine System in Humans -- Endocannabinoid System -- Glutamate Receptors (Metabotropic) -- Histamine H3 Receptors -- Hormone Receptors (Steroids) -- Monoamine Oxidase B -- MRP1 Function in the BBB -- Neuroinflammation: From Target Selection to Preclinical and Clinical Studies -- Nicotinic Acetylcholine Receptors -- NMDA Receptors -- Norepinephrine Transporter -- Opioid Receptors -- P-Glycoprotein and Other ABC Transporters -- Phosphodiesterases -- Purinergic Receptors -- Serotonin System -- Serotonin Transporter and Monoamine Oxidase A -- Sigma-1 Receptors -- Sigma-2 Receptors -- Synaptic Density (SV2A) -- Tau Pathology -- Translocator Protein -- Tropomyosin Receptor Kinase -- Vesicular Acetylcholine Transporter -- Vesicular Monoamine Transporter.
This book, now in a fully updated second edition, is a comprehensive and up-to-date guide to the use of PET and SPECT for the imaging of neurobiological systems. Diverse aspects of neurotransmission in the brain are discussed, such as visualization and quantification of neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, B-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. A wide range of systems not addressed in the first edition are covered, reflecting the advances made in recent years. The book combines the expertise of authors internationally renowned for their dedication to the development of novel probes and techniques for the investigation of neurobiological systems. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all with an interest in clinical and preclinical neuroscience. Companion volumes on the use of PET and SPECT in neurology and psychiatry complete a trilogy.
ISBN: 9783030531768$q(electronic bk.)
Standard No.: 10.1007/978-3-030-53176-8doiSubjects--Topical Terms:
276849
Tomography, Emission.
LC Class. No.: RC78.7.T62
Dewey Class. No.: 616.07575
National Library of Medicine Call No.: WN 206
PET and SPECT of neurobiological systems
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PART I BASICS: Animal Models for Brain Research -- Small Animal Molecular Imaging - uPET, uSPECT -- Cerebral Glucose Metabolism -- Cerebral Blood Flow Measurement with 15O-Water PET -- Principles of Brain Perfusion SPECT -- The Impact of Genetic Polymorphisms on Neuroreceptor Imaging -- PART II SYSTEMS: Acetylcholinesterase -- Adenosine Receptors -- Beta-Amyloid and Other Proteinopathies -- Central Benzodiazepine Receptors -- Cyclooxygenase-2 -- Dopamine System in Humans -- Endocannabinoid System -- Glutamate Receptors (Metabotropic) -- Histamine H3 Receptors -- Hormone Receptors (Steroids) -- Monoamine Oxidase B -- MRP1 Function in the BBB -- Neuroinflammation: From Target Selection to Preclinical and Clinical Studies -- Nicotinic Acetylcholine Receptors -- NMDA Receptors -- Norepinephrine Transporter -- Opioid Receptors -- P-Glycoprotein and Other ABC Transporters -- Phosphodiesterases -- Purinergic Receptors -- Serotonin System -- Serotonin Transporter and Monoamine Oxidase A -- Sigma-1 Receptors -- Sigma-2 Receptors -- Synaptic Density (SV2A) -- Tau Pathology -- Translocator Protein -- Tropomyosin Receptor Kinase -- Vesicular Acetylcholine Transporter -- Vesicular Monoamine Transporter.
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This book, now in a fully updated second edition, is a comprehensive and up-to-date guide to the use of PET and SPECT for the imaging of neurobiological systems. Diverse aspects of neurotransmission in the brain are discussed, such as visualization and quantification of neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, B-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. A wide range of systems not addressed in the first edition are covered, reflecting the advances made in recent years. The book combines the expertise of authors internationally renowned for their dedication to the development of novel probes and techniques for the investigation of neurobiological systems. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all with an interest in clinical and preclinical neuroscience. Companion volumes on the use of PET and SPECT in neurology and psychiatry complete a trilogy.
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