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Handbook of traumatic brain injury a...

Castellani, Rudy J.

Handbook of traumatic brain injury and neurodegeneration

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Handbook of traumatic brain injury and neurodegenerationRudy J. Castellani.
其他作者:	Castellani, Rudy J.
出版者:	Washington :IOS Press,2020.
面頁冊數:	1 online resource (xiii, 490 p.)
標題:	BrainWounds and injuries.
電子資源:	http://ebooks.windeal.com.tw/ios/cover.asp?isbn=9781643680644
ISBN:	9781643680651 (ebk.)

Handbook of traumatic brain injury and neurodegeneration
Handbook of traumatic brain injury and neurodegeneration[electronic resource] /Rudy J. Castellani. - Washington :IOS Press,2020. - 1 online resource (xiii, 490 p.) - Advances in alzheimer's disease ;volume 7. - Advances in Alzheimer's disease (Series) ;v. 3..

ncludes bibliographical references and indexes.

"Holbourne's theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood 'punch drunk' syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field"--

ISBN: 9781643680651 (ebk.)

LCCN: 2020936247Subjects--Topical Terms:

483852
Brain
--Wounds and injuries.

LC Class. No.: RD594 / .H36 2020

Dewey Class. No.: 617.4/81044

Handbook of traumatic brain injury and neurodegeneration
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245 0 0 $a Handbook of traumatic brain injury and neurodegeneration $h [electronic resource] / $c Rudy J. Castellani.
260 $a Washington : $b IOS Press, $c 2020.
300 $a 1 online resource (xiii, 490 p.)
490 0 $a Advances in alzheimer's disease ; $v volume 7
504 $a ncludes bibliographical references and indexes.
520 $a "Holbourne's theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood 'punch drunk' syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field"-- $c Provided by publisher.
650 0 $a Brain $x Wounds and injuries. $3 483852
650 0 $a Nervous system $x Degeneration. $3 195201
700 1 $a Castellani, Rudy J. $3 900267
830 0 $a Advances in Alzheimer's disease (Series) ; $v v. 3. $3 718027
856 4 0 $u http://ebooks.windeal.com.tw/ios/cover.asp?isbn=9781643680644