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Ferroptosismechanism and diseases /

Alborzinia, Hamed.

Ferroptosismechanism and diseases /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Ferroptosisedited by Andres F. Florez, Hamed Alborzinia.
其他題名:	mechanism and diseases /
其他作者:	Florez, Andres F.
出版者:	Cham :Springer International Publishing :2021.
面頁冊數:	ix, 140 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Cell death.
電子資源:	https://doi.org/10.1007/978-3-030-62026-4
ISBN:	9783030620264

Ferroptosismechanism and diseases /
Ferroptosismechanism and diseases /[electronic resource] :edited by Andres F. Florez, Hamed Alborzinia. - Cham :Springer International Publishing :2021. - ix, 140 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.13012214-8019 ;. - Advances in experimental medicine and biology ;946..

Foreword -- Ferroptosis: Concepts and Definitions -- Overcoming Therapeutic Challenges for Pancreatic Ductal Adenocarcinoma with xCT inhibitors -- Iron Homeostasis and Metabolism: Two Sides of a Coin -- The Role of NCOA4-mediated Ferritinophagy in Ferroptosis -- Emerging Role for Ferroptosis in Infectious Diseases -- Small Molecule Regulators of Ferroptosis -- Necroptosis, The other main Caspase-Independent Cell Death.

This book focuses on the emerging role of ferroptosis in human diseases. It gives a detailed perspective on how to induce or suppress ferroptosis to treat challenging conditions such as infectious diseases, including COVID-19, tuberculosis, parasitic diseases and cancer. The book serves as a practical guide by providing a valuable collection of all currently known activators or inhibitors of ferroptosis. It will enable readers to choose molecules for experimental design for in vitro and in vivo studies of ferroptosis. Furthermore, this volume highlights the aspects of iron metabolism and its connection to ferritinophagy, a ferritin selective autophagy, with profound implications in neurodegenerative diseases such as Alzheimer, Parkinson, Huntington and ALS. Lastly, it describes necroptosis, another important form of cell death, along with its connections to human disorders and potential crosstalk with ferroptosis. While covering basic concepts, the book delves into mechanisms and modulation of ferroptosis for treating a wide variety of human diseases thus offering a valuable and informative resource for both, scientists and clinical researchers.

ISBN: 9783030620264

Standard No.: 10.1007/978-3-030-62026-4doiSubjects--Topical Terms:

193735
Cell death.

LC Class. No.: QH671

Dewey Class. No.: 571.936

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520 $a This book focuses on the emerging role of ferroptosis in human diseases. It gives a detailed perspective on how to induce or suppress ferroptosis to treat challenging conditions such as infectious diseases, including COVID-19, tuberculosis, parasitic diseases and cancer. The book serves as a practical guide by providing a valuable collection of all currently known activators or inhibitors of ferroptosis. It will enable readers to choose molecules for experimental design for in vitro and in vivo studies of ferroptosis. Furthermore, this volume highlights the aspects of iron metabolism and its connection to ferritinophagy, a ferritin selective autophagy, with profound implications in neurodegenerative diseases such as Alzheimer, Parkinson, Huntington and ALS. Lastly, it describes necroptosis, another important form of cell death, along with its connections to human disorders and potential crosstalk with ferroptosis. While covering basic concepts, the book delves into mechanisms and modulation of ferroptosis for treating a wide variety of human diseases thus offering a valuable and informative resource for both, scientists and clinical researchers.
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