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Biology and treatment of leukemia an...

Marcucci, Guido.

Biology and treatment of leukemia and bone marrow neoplasms

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Biology and treatment of leukemia and bone marrow neoplasmsedited by Vinod Pullarkat, Guido Marcucci.
其他作者:	Pullarkat, Vinod.
出版者:	Cham :Springer International Publishing :2021.
面頁冊數:	viii, 196 p. :ill. (chiefly col.), digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Acute leukemia.
電子資源:	https://doi.org/10.1007/978-3-030-78311-2
ISBN:	9783030783112$q(electronic bk.)

Biology and treatment of leukemia and bone marrow neoplasms
Biology and treatment of leukemia and bone marrow neoplasms[electronic resource] /edited by Vinod Pullarkat, Guido Marcucci. - Cham :Springer International Publishing :2021. - viii, 196 p. :ill. (chiefly col.), digital ;24 cm. - Cancer treatment and research,v. 1812509-8497 ;. - Cancer treatment and research ;v. 114..

Advances in diagnosis and risk stratification of leukemias and bone marrow neoplasms -- Genetics and diagnostic approach to lymphoblastic leukemia -- Acute promyelocytic leukemia: update on risk stratification and treatment -- Current and emerging therapies for AML -- Current management and new developments in treatment of ALL -- Contemporary therapy of CML -- MDS: Pathogenesis and therapy -- Chronic lymphocytic leukemia: Biology and therapy -- Biology and current treatment of Myeloproliferative neoplasms -- Systemic Mastocytosis: Pathology and treatment -- Adoptive T-cell therapy and other novel immunotherapies for leukemia.

This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.

ISBN: 9783030783112$q(electronic bk.)

Standard No.: 10.1007/978-3-030-78311-2doiSubjects--Topical Terms:

887847
Acute leukemia.

LC Class. No.: RC643 / .B56 2021

Dewey Class. No.: 616.99419

Biology and treatment of leukemia and bone marrow neoplasms
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520 $a This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.
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