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Introduction to proteomics :tools for the new biology /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Introduction to proteomics :by Daniel C. Liebler ; foreword by John R. Yates, III.
其他題名:	tools for the new biology /
作者:	Liebler, Daniel C.
出版者:	Totowa, NJ :Humana Press,©2002.
面頁冊數:	ix, 198 pages :illustrations (some color) ;21 cm
標題:	Protéomique.
電子資源:	http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=71291
電子資源:	http://catdir.loc.gov/catdir/toc/fy034/2001051465.html
電子資源:	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=009712603&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
電子資源:	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=009712603&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
電子資源:	http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=71291
ISBN:	0585418799

Introduction to proteomics :tools for the new biology /
Liebler, Daniel C.

Introduction to proteomics :tools for the new biology /by Daniel C. Liebler ; foreword by John R. Yates, III. - Totowa, NJ :Humana Press,©2002. - ix, 198 pages :illustrations (some color) ;21 cm

Includes bibliographical references and index.

Proteomics and the New Biology -- The Proteome -- Overview of Analytical Proteomics -- Analytical Protein and Peptide Separations -- Protein Digestion Techniques -- Mass Spectrometersfor Protein and Peptide Analysis -- Protein Identification by Peptide Mass Fingerprinting -- Peptide Sequence Analysis by Tandem Mass Spectrometry -- Protein Identification with Tandem Mass Spectrometry Data -- SALSA: An Algorithmfor Mining Specific Features of Tandem MS Data -- Mining Proteomes -- Protein Expression Profiling -- Identifying Protein-Protein Interactions and Protein Complexes -- Mapping Protein Modifications -- New Directions in Proteomics.

Advances in genome sequencing, analytical instrumentation, and computing power have excitingly transformed the practice of biology by now making it possible to understand complex biological systems as collections of proteins-proteomes. In Introduction to Proteomics: Tools for the New Biology, Daniel C. Liebler masterfully introduces the science of proteomics by spelling out the basics of how one analyzes proteins and proteomes, and just how these approaches are then employed to investigate their roles in living systems. He explains the key concepts of proteomics, how the analytical instrumentation works, what data mining and other software tools do, and how these tools can be integrated to study proteomes. Also discussed are how protein and peptide separation techniques are applied in proteomics, how mass spectrometry is used to identify proteins, and how data analysis software enables protein identification and the mapping of modifications. In addition, there are proteomic approaches for analyzing differential protein expression, characterizing proteomic diversity, and dissecting protein-protein interactions and networks. Comprehensive, concise, and easy-to-read, Introduction to Proteomics: Tools for the New Biology provides researchers new to proteomics with all the essential concepts and background needed to use the powerful new proteomic techniques in their research, to make intelligent requests to proteomics service facilities, and to better understand and utilize the rapidly growing proteomics literature.

English.

ISBN: 0585418799

LCCN: 2001051465

Nat. Bib. No.: GBA341373bnbSubjects--Topical Terms:

918536
Protéomique.

LC Class. No.: QP551 / .L467 2002

Dewey Class. No.: 572/.6/072

Universal Decimal Class. No.: 577.112 P2

National Agricultural Library Call No.: QP551 / .L467 2002

National Library of Medicine Call No.: 2004 F-201

Introduction to proteomics :tools for the new biology /
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