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Molecular imaging and targeted therapyradiopharmaceuticals and clinical applications /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Molecular imaging and targeted therapyby Shankar Vallabhajosula.
其他題名:	radiopharmaceuticals and clinical applications /
作者:	Vallabhajosula, Shankar.
出版者:	Cham :Springer International Publishing :2023.
面頁冊數:	xxv, 708 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Radiopharmaceuticals.
電子資源:	https://doi.org/10.1007/978-3-031-23205-3
ISBN:	9783031232053$q(electronic bk.)

Molecular imaging and targeted therapyradiopharmaceuticals and clinical applications /
Vallabhajosula, Shankar.

Molecular imaging and targeted therapyradiopharmaceuticals and clinical applications /[electronic resource] :by Shankar Vallabhajosula. - Second edition. - Cham :Springer International Publishing :2023. - xxv, 708 p. :ill., digital ;24 cm.

Molecular Imaging and Targeted Therapy: Introduction -- Atomism and Radioactivity: A Brief History -- Atoms and Radiation -- Radioactivity -- Production of Radionuclides -- PET and SPECT Scanners -- Chemistry: Basic Principles -- Cell and Molecular Biology -- Radiopharmaceuticals -- Chemistry of Organic Radionuclides (C, N, and O) -- Chemistry of Radiohalogens (F, Br, I, and At) -- Chemistry of Trivalent Metals Radionuclides (Ga, In, Y, Lu) -- Chemistry of Transition Metals (Cu, Zr, Tc, Re) -- Quality Control of Radiopharmaceuticals -- Pharmacokinetics and Modeling -- Molecular Imaging in Oncology -- Molecular Imaging in Neurology and Psychiatry -- Molecular Imaging in Cardiology -- Molecular Imaging of Gene Expression and Cell Trafficking -- Radiation Dosimetry and Protection -- Radiopharmaceuticals for Targeted Therapy -- Targeted Therapy with Beta Emitting Radiopharmaceuticals -- Targeted Therapy with Alpha Emitting Radiopharmaceuticals -- Theranostics: Molecular Imaging and Targeted Therapy -- Radiopharmaceuticals: Drug Development and Regulatory Issues.

This book, now published in its second edition, covers a wide range of topics relating to the use of radiopharmaceuticals. The basics of nuclear chemistry, radiochemistry, and radiopharmacology are considered in detail, regulatory issues are reviewed, and potential applications in drug development, translational medicine, clinical diagnostics, and targeted therapy are discussed. Compared with the first edition, the chapters on targeted therapy with alpha- and beta-emitting radiopharmaceuticals and theranostics are completely new. Other chapters have been updated and revised as necessary. Radioisotope-based molecular imaging probes (radiopharmaceuticals) provide unprecedented insights into biochemistry and function in both normal and diseased states of living systems, with unbiased in vivo measurements of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology, including functional magnetic resonance imaging, can provide such high sensitivity and specificity at a tracer level. This book, written by an experienced radiochemist and scientist, offers valuable insights into the full range of applications of this technology.

ISBN: 9783031232053$q(electronic bk.)

Standard No.: 10.1007/978-3-031-23205-3doiSubjects--Topical Terms:

347769
Radiopharmaceuticals.

LC Class. No.: RM852

Dewey Class. No.: 616.07575

Molecular imaging and targeted therapyradiopharmaceuticals and clinical applications /
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505 0 $a Molecular Imaging and Targeted Therapy: Introduction -- Atomism and Radioactivity: A Brief History -- Atoms and Radiation -- Radioactivity -- Production of Radionuclides -- PET and SPECT Scanners -- Chemistry: Basic Principles -- Cell and Molecular Biology -- Radiopharmaceuticals -- Chemistry of Organic Radionuclides (C, N, and O) -- Chemistry of Radiohalogens (F, Br, I, and At) -- Chemistry of Trivalent Metals Radionuclides (Ga, In, Y, Lu) -- Chemistry of Transition Metals (Cu, Zr, Tc, Re) -- Quality Control of Radiopharmaceuticals -- Pharmacokinetics and Modeling -- Molecular Imaging in Oncology -- Molecular Imaging in Neurology and Psychiatry -- Molecular Imaging in Cardiology -- Molecular Imaging of Gene Expression and Cell Trafficking -- Radiation Dosimetry and Protection -- Radiopharmaceuticals for Targeted Therapy -- Targeted Therapy with Beta Emitting Radiopharmaceuticals -- Targeted Therapy with Alpha Emitting Radiopharmaceuticals -- Theranostics: Molecular Imaging and Targeted Therapy -- Radiopharmaceuticals: Drug Development and Regulatory Issues.
520 $a This book, now published in its second edition, covers a wide range of topics relating to the use of radiopharmaceuticals. The basics of nuclear chemistry, radiochemistry, and radiopharmacology are considered in detail, regulatory issues are reviewed, and potential applications in drug development, translational medicine, clinical diagnostics, and targeted therapy are discussed. Compared with the first edition, the chapters on targeted therapy with alpha- and beta-emitting radiopharmaceuticals and theranostics are completely new. Other chapters have been updated and revised as necessary. Radioisotope-based molecular imaging probes (radiopharmaceuticals) provide unprecedented insights into biochemistry and function in both normal and diseased states of living systems, with unbiased in vivo measurements of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology, including functional magnetic resonance imaging, can provide such high sensitivity and specificity at a tracer level. This book, written by an experienced radiochemist and scientist, offers valuable insights into the full range of applications of this technology.
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