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Affinity and efficacythe components ...

Ehlert, Frederick J.

Affinity and efficacythe components of drug-receptor interactions /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Affinity and efficacyFrederick J. Ehlert.
Reminder of title:	the components of drug-receptor interactions /
remainder title:	Components of drug-receptor interactions
Author:	Ehlert, Frederick J.
Published:	New Jersey :World Scientific,2014.
Description:	1 online resource.
Subject:	Drug receptors.
Online resource:	http://www.worldscientific.com/worldscibooks/10.1142/7888#t=toc
ISBN:	9789814324229$q(electronic bk.)

Affinity and efficacythe components of drug-receptor interactions /
Ehlert, Frederick J.

Affinity and efficacythe components of drug-receptor interactions /[electronic resource] :Components of drug-receptor interactionsFrederick J. Ehlert. - New Jersey :World Scientific,2014. - 1 online resource.

Includes bibliographical references.

Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.

ISBN: 9789814324229$q(electronic bk.)Subjects--Topical Terms:

303325
Drug receptors.

LC Class. No.: RM302.4

Dewey Class. No.: 615.7/0452

National Library of Medicine Call No.: QV 36

Affinity and efficacythe components of drug-receptor interactions /
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100 1 $a Ehlert, Frederick J. $3 716997
245 1 0 $a Affinity and efficacy $h [electronic resource] : $b the components of drug-receptor interactions / $c Frederick J. Ehlert.
246 1 $a Components of drug-receptor interactions
260 $a New Jersey : $b World Scientific, $c 2014.
300 $a 1 online resource.
504 $a Includes bibliographical references.
505 0 $a Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.
588 0 $a Print version record.
650 0 $a Drug receptors. $3 303325
650 0 $a Drugs $x Effectiveness. $3 680691
650 0 $a Drug-nutrient interactions. $3 302350
650 0 $a Pharmaceutical chemistry. $3 203135
650 1 2 $a Receptors, Drug. $3 229907
650 2 2 $a Ligand-Gated Ion Channels. $3 716998
650 2 2 $a Protein Binding. $3 467726
650 2 2 $a Radioligand Assay. $3 716999
650 2 2 $a Receptors, G-Protein-Coupled. $3 302773
856 4 0 $u http://www.worldscientific.com/worldscibooks/10.1142/7888#t=toc