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Targeting protein-protein interactio...

Georg, Gunda I.

Targeting protein-protein interactions by small molecules

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Targeting protein-protein interactions by small moleculesedited by Chunquan Sheng, Gunda I. Georg.
其他作者:	Sheng, Chunquan.
出版者:	Singapore :Springer Singapore :2018.
面頁冊數:	xi, 329 p. :digital ;24 cm.
Contained By:	Springer eBooks
標題:	Protein-protein interactions.
電子資源:	http://dx.doi.org/10.1007/978-981-13-0773-7
ISBN:	9789811307737$q(electronic bk.)

Targeting protein-protein interactions by small molecules
Targeting protein-protein interactions by small molecules[electronic resource] /edited by Chunquan Sheng, Gunda I. Georg. - Singapore :Springer Singapore :2018. - xi, 329 p. :digital ;24 cm.

This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.

ISBN: 9789811307737$q(electronic bk.)

Standard No.: 10.1007/978-981-13-0773-7doiSubjects--Topical Terms:

265915
Protein-protein interactions.

LC Class. No.: QP551.5 / .T374 2018

Dewey Class. No.: 572.64

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520 $a This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design. The second part presents recent advances in small molecule inhibitors, focusing on clinical candidates and new PPI targets. This book has broad appeal and is of significant interest to the pharmaceutical science and medicinal chemistry communities.
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