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The search for human chromosomesa history of discovery /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The search for human chromosomesby Wilson John Wall.
其他題名:	a history of discovery /
作者:	Wall, Wilson John.
出版者:	Cham :Springer International Publishing :2016.
面頁冊數:	vii, 179 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Human chromosomes.
電子資源:	http://dx.doi.org/10.1007/978-3-319-26336-6
ISBN:	9783319263366$q(electronic bk.)

The search for human chromosomesa history of discovery /
Wall, Wilson John.

The search for human chromosomesa history of discovery /[electronic resource] :by Wilson John Wall. - Cham :Springer International Publishing :2016. - vii, 179 p. :ill., digital ;24 cm.

Introduction -- Background to the Hunt for the Human Chromosome Number -- Microscopes and Stains: The Rise of Technology -- Mendel and Genetics -- Chromosomes as the Carriers of Heredity -- Difficulties of Chromosome Handling and Access to Material -- The Implications of DNA Structure -- Tissue Culture and the Cell Cycle: The Answer is Revealed -- The Flowering of Clinical Genetics -- Sex and Chromosomes -- What we Know, What we Don't and Where This may Lead us -- Appendix A: Rough Guide to Chromosome Structure -- Appendix B: People in the Text -- Glossary.

This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book.

ISBN: 9783319263366$q(electronic bk.)

Standard No.: 10.1007/978-3-319-26336-6doiSubjects--Topical Terms:

739131
Human chromosomes.

LC Class. No.: QH431

Dewey Class. No.: 599.935

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505 0 $a Introduction -- Background to the Hunt for the Human Chromosome Number -- Microscopes and Stains: The Rise of Technology -- Mendel and Genetics -- Chromosomes as the Carriers of Heredity -- Difficulties of Chromosome Handling and Access to Material -- The Implications of DNA Structure -- Tissue Culture and the Cell Cycle: The Answer is Revealed -- The Flowering of Clinical Genetics -- Sex and Chromosomes -- What we Know, What we Don't and Where This may Lead us -- Appendix A: Rough Guide to Chromosome Structure -- Appendix B: People in the Text -- Glossary.
520 $a This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book.
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