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Aging mechanismslongevity, metabolis...

Mook-Jung, Inhee.

Aging mechanismslongevity, metabolism, and brain aging /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Aging mechanismsedited by Nozomu Mori, Inhee Mook-Jung.
其他題名:	longevity, metabolism, and brain aging /
其他作者:	Mori, Nozomu.
出版者:	Tokyo :Springer Japan :2015.
面頁冊數:	xiv, 439 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	AgingPhysiological aspects.
電子資源:	http://dx.doi.org/10.1007/978-4-431-55763-0
ISBN:	9784431557630$q(electronic bk.)

Aging mechanismslongevity, metabolism, and brain aging /
Aging mechanismslongevity, metabolism, and brain aging /[electronic resource] :edited by Nozomu Mori, Inhee Mook-Jung. - Tokyo :Springer Japan :2015. - xiv, 439 p. :ill., digital ;24 cm.

Preface -- Part I From Hypotheses to Mechanisms -- Part II Human Longevity: Centenarianism and Progeria -- Part III Stem Cells, Cultured Neurons, and Lower Animal Models -- Part IV Metabolism: Factors Affecting Tissue Aging -- Part V Aging Brain: Adult Neurogenesis, Synaptic Plasticity, and Brain Volume -- Part VI Aged Brain: Mechanisms of Neurodegeneration -- Part VII Anti-Brain Aging: Neuroprotection and Therapeutic Approaches -- Epilogue -- Appendix -- Index.

This book brings together the most up-to-date information on recent research results of leading laboratories on aging science in East Asia, particularly in Japan, Korea, and Hong Kong. Starting with a comprehensive overview of various hypotheses on biological mechanisms of aging by Dr. Sataro Goto, each chapter covers broad aspects of the most recent findings in aging-related topics: centenarian studies and genome analysis of progeria, metabolic biochemistry and neurobiology, longevity controls in yeast and nematodes, oxidative stress and calorie restriction, and neurodegeneration mechanisms in Alzheimer's and Huntington's diseases, with further potential therapeutic approaches to these age-related neurodegenerative diseases. Also included, in part, is a summary and the outcomes of a scientific discussion forum called the Asian Aging Core for Longevity (AACL) that has been held annually alternating between Japan and Korea during the last decade. This book can serve as a useful resource for finding appropriate collaborators in the areas it covers. The target readership is made up of graduate students and researchers at universities, medical and/or life-science schools, and biomedical and pharmaceutical institutes. Why does aging exist? How do we age? How is each organism's lifespan determined? These are fundamental questions in the field. We may be still far from achieving a complete view of aging mechanisms, but this book, Aging Mechanisms, offers an excellent opportunity to become familiar with the most updated progress in the biomedical research of aging in Japan and Korea, the two leading nations for human longevity.

ISBN: 9784431557630$q(electronic bk.)

Standard No.: 10.1007/978-4-431-55763-0doiSubjects--Topical Terms:

229395
Aging
--Physiological aspects.

LC Class. No.: QP86

Dewey Class. No.: 612.67

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