國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁 到查詢結果 [ subject:"Nucleic Acid Chemistry." ]

切換: 標籤 | MARC模式 | ISBD

Catalytically active nucleic acids

Seitz, Harald.

Catalytically active nucleic acids

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Catalytically active nucleic acidsedited by Harald Seitz, Frank Stahl, Johanna-Gabriela Walter.
其他作者:	Seitz, Harald.
出版者:	Cham :Springer International Publishing :2020.
面頁冊數:	vii, 123 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Nucleic acids.
電子資源:	https://doi.org/10.1007/978-3-030-29646-9
ISBN:	9783030296469$q(electronic bk.)

Catalytically active nucleic acids
Catalytically active nucleic acids[electronic resource] /edited by Harald Seitz, Frank Stahl, Johanna-Gabriela Walter. - Cham :Springer International Publishing :2020. - vii, 123 p. :ill., digital ;24 cm. - Advances in biochemical engineering/biotechnology,1700724-6145 ;. - Advances in biochemical engineering/biotechnology ;138..

RNA G-Quadruplexes as key Motifs of the Transcriptome -- Challenges and Perspectives in Nucleic Acid Enzyme Engineering -- Strategies for Characterization of Enzymatic Nucleic Acids -- Bioanalytical Application of Peroxidase Mimicking DNAzymes: Status and Challenges -- Hemin/G-Quadruplex Horseradish Peroxidase-Mimicking DNAzyme: Principle and Biosensing Application -- Aptazymes: Expanding the Specificity of Natural Catalytic Nucleic Acids by Application of In Vitro Selected Oligonucleotides.

This volume reviews numerous reaction mechanisms and applications of nucleic acids with catalytic activity. Written by an interdisciplinary team of authors, it provides an essential overview of these acids' fundamental aspects, while also addressing associated methodologies such as nucleic acid enzyme engineering, peroxidase-mimicking DNAzymes and Aptazymes. After the discovery of natural ribozymes - RNA molecules that mediate the cleavage and formation of phosphodiester bonds and the formation of peptide bonds - numerous artificial ribozymes with altered catalytic activities were produced by in vitro and in vivo selection. Unlike ribozymes, DNAzymes do not occur in nature. Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes. The key advantages of these enzymes: they are e.g. smaller, easier to produce and purify than proteins, and can withstand denaturation, e.g. by heat. Over the last few years, the number of publications on the applications of enzymatic nucleic acids has grown steadily. Summarizing the fundamentals and applications of these acids, this book will not only be an excellent resource for experts in the field but will also guide young researchers just starting out in this significant area.

ISBN: 9783030296469$q(electronic bk.)

Standard No.: 10.1007/978-3-030-29646-9doiSubjects--Topical Terms:

194925
Nucleic acids.

LC Class. No.: QP551

Dewey Class. No.: 572.8

Catalytically active nucleic acids
LDR:02945nmm a2200337 a 4500 001 577593
003 DE-He213
005 20200221145457.0
006 m d
007 cr nn 008maaau
008 201203s2020 sz s 0 eng d
020 $a 9783030296469$q(electronic bk.)
020 $a 9783030296452$q(paper)
024 7 $a 10.1007/978-3-030-29646-9 $2 doi
035 $a 978-3-030-29646-9
040 $a GP $c GP
041 0 $a eng
050 4 $a QP551
072 7 $a TC $2 bicssc
072 7 $a TEC009010 $2 bisacsh
072 7 $a TC $2 thema
082 0 4 $a 572.8 $2 23
090 $a QP551 $b .C357 2020
245 0 0 $a Catalytically active nucleic acids $h [electronic resource] / $c edited by Harald Seitz, Frank Stahl, Johanna-Gabriela Walter.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2020.
300 $a vii, 123 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in biochemical engineering/biotechnology, $x 0724-6145 ; $v 170
505 0 $a RNA G-Quadruplexes as key Motifs of the Transcriptome -- Challenges and Perspectives in Nucleic Acid Enzyme Engineering -- Strategies for Characterization of Enzymatic Nucleic Acids -- Bioanalytical Application of Peroxidase Mimicking DNAzymes: Status and Challenges -- Hemin/G-Quadruplex Horseradish Peroxidase-Mimicking DNAzyme: Principle and Biosensing Application -- Aptazymes: Expanding the Specificity of Natural Catalytic Nucleic Acids by Application of In Vitro Selected Oligonucleotides.
520 $a This volume reviews numerous reaction mechanisms and applications of nucleic acids with catalytic activity. Written by an interdisciplinary team of authors, it provides an essential overview of these acids' fundamental aspects, while also addressing associated methodologies such as nucleic acid enzyme engineering, peroxidase-mimicking DNAzymes and Aptazymes. After the discovery of natural ribozymes - RNA molecules that mediate the cleavage and formation of phosphodiester bonds and the formation of peptide bonds - numerous artificial ribozymes with altered catalytic activities were produced by in vitro and in vivo selection. Unlike ribozymes, DNAzymes do not occur in nature. Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes. The key advantages of these enzymes: they are e.g. smaller, easier to produce and purify than proteins, and can withstand denaturation, e.g. by heat. Over the last few years, the number of publications on the applications of enzymatic nucleic acids has grown steadily. Summarizing the fundamentals and applications of these acids, this book will not only be an excellent resource for experts in the field but will also guide young researchers just starting out in this significant area.
650 0 $a Nucleic acids. $3 194925
650 1 4 $a Biochemical Engineering. $3 274179
650 2 4 $a Nucleic Acid Chemistry. $3 376665
650 2 4 $a Enzymology. $3 193702
700 1 $a Seitz, Harald. $3 259920
700 1 $a Stahl, Frank. $3 866036
700 1 $a Walter, Johanna-Gabriela. $3 866037
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a Advances in biochemical engineering/biotechnology ; $v 138. $3 677812
856 4 0 $u https://doi.org/10.1007/978-3-030-29646-9
950 $a Chemistry and Materials Science (Springer-11644)