語系:
繁體中文
English
說明(常見問題)
圖資館首頁
登入
回首頁
到查詢結果
[ subject:"Nucleic Acid Chemistry." ]
切換:
標籤
|
MARC模式
|
ISBD
RNA damage and repair
~
Kotta-Loizou, Ioly.
RNA damage and repair
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
RNA damage and repairedited by Ioly Kotta-Loizou.
其他作者:
Kotta-Loizou, Ioly.
出版者:
Cham :Springer International Publishing :2021.
面頁冊數:
ix, 178 p. :ill., digital ;24 cm.
Contained By:
Springer Nature eBook
標題:
RNA.
電子資源:
https://doi.org/10.1007/978-3-030-76571-2
ISBN:
9783030765712$q(electronic bk.)
RNA damage and repair
RNA damage and repair
[electronic resource] /edited by Ioly Kotta-Loizou. - Cham :Springer International Publishing :2021. - ix, 178 p. :ill., digital ;24 cm.
Part 1: RNA Damage and Repair in Prokaryotes -- Chapter 1: Endoribonucleases of the toxin-antitoxin systems induce abortive infection -- Chapter 2: The lifecycle of ribosomal RNA in bacteria -- Chapter 3: The Rtc RNA end healing and sealing system -- Part 2: RNA Damage and Repair in Eukaryotes -- Chapter 4: Oxidative and nitrative RNA modifications in plants -- Chapter 5: The role of ribonucleases in RNA damage, inactivation, and degradation -- Chapter 6: Cytoplasmic mRNA recapping: An unexpected form of RNA repair -- Part 3: RNA Damage in Human Diseases -- Chapter 7: Adenosine-to-Inosine RNA editing: a key RNA processing step rewriting transcriptome in normal physiology and diseases -- Chapter 8: RNA-mediated metabolic defects in microsatellite expansion diseases.
Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DNA), where genetic information is stored, and proteins, which perform the necessary functions within the cell. Traditionally, the structural and functional properties of RNA are closely linked to gene expression. However, RNA-based enzymes, called ribozymes, are also involved in catalysis and small RNAs regulate key cellular processes, such as cell growth, division, differentiation, aging and death. RNA is a sensitive macromolecule that can be easily damaged by environmental conditions (ultraviolet radiation, oxidative stress) and biological factors (ribonucleases, ribotoxins, CRISPR-Cas systems) Therefore, cells have developed mechanisms to protect and/or repair RNA molecules. This book presents an overview of the biology of RNA damage, protection and repair in prokaryotes and eukaryotes. Individual chapters cover the expression regulation, enzymology and physiological role of such systems, and link them to important human diseases such as cancer and degenerative diseases.
ISBN: 9783030765712$q(electronic bk.)
Standard No.: 10.1007/978-3-030-76571-2doiSubjects--Topical Terms:
216963
RNA.
LC Class. No.: QP623
Dewey Class. No.: 572.88
RNA damage and repair
LDR
:02868nmm a2200325 a 4500
001
601845
003
DE-He213
005
20210705134945.0
006
m d
007
cr nn 008maaau
008
211112s2021 sz s 0 eng d
020
$a
9783030765712$q(electronic bk.)
020
$a
9783030765705$q(paper)
024
7
$a
10.1007/978-3-030-76571-2
$2
doi
035
$a
978-3-030-76571-2
040
$a
GP
$c
GP
041
0
$a
eng
050
4
$a
QP623
072
7
$a
PSB
$2
bicssc
072
7
$a
SCI007000
$2
bisacsh
072
7
$a
PSB
$2
thema
082
0 4
$a
572.88
$2
23
090
$a
QP623
$b
.R627 2021
245
0 0
$a
RNA damage and repair
$h
[electronic resource] /
$c
edited by Ioly Kotta-Loizou.
260
$a
Cham :
$b
Springer International Publishing :
$b
Imprint: Springer,
$c
2021.
300
$a
ix, 178 p. :
$b
ill., digital ;
$c
24 cm.
505
0
$a
Part 1: RNA Damage and Repair in Prokaryotes -- Chapter 1: Endoribonucleases of the toxin-antitoxin systems induce abortive infection -- Chapter 2: The lifecycle of ribosomal RNA in bacteria -- Chapter 3: The Rtc RNA end healing and sealing system -- Part 2: RNA Damage and Repair in Eukaryotes -- Chapter 4: Oxidative and nitrative RNA modifications in plants -- Chapter 5: The role of ribonucleases in RNA damage, inactivation, and degradation -- Chapter 6: Cytoplasmic mRNA recapping: An unexpected form of RNA repair -- Part 3: RNA Damage in Human Diseases -- Chapter 7: Adenosine-to-Inosine RNA editing: a key RNA processing step rewriting transcriptome in normal physiology and diseases -- Chapter 8: RNA-mediated metabolic defects in microsatellite expansion diseases.
520
$a
Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DNA), where genetic information is stored, and proteins, which perform the necessary functions within the cell. Traditionally, the structural and functional properties of RNA are closely linked to gene expression. However, RNA-based enzymes, called ribozymes, are also involved in catalysis and small RNAs regulate key cellular processes, such as cell growth, division, differentiation, aging and death. RNA is a sensitive macromolecule that can be easily damaged by environmental conditions (ultraviolet radiation, oxidative stress) and biological factors (ribonucleases, ribotoxins, CRISPR-Cas systems) Therefore, cells have developed mechanisms to protect and/or repair RNA molecules. This book presents an overview of the biology of RNA damage, protection and repair in prokaryotes and eukaryotes. Individual chapters cover the expression regulation, enzymology and physiological role of such systems, and link them to important human diseases such as cancer and degenerative diseases.
650
0
$a
RNA.
$3
216963
650
0
$a
DNA damage.
$3
229562
650
1 4
$a
Nucleic Acid Chemistry.
$3
376665
650
2 4
$a
Enzymology.
$3
193702
650
2 4
$a
Cell Biology.
$3
274165
650
2 4
$a
Microbiology.
$3
192943
700
1
$a
Kotta-Loizou, Ioly.
$3
897417
710
2
$a
SpringerLink (Online service)
$3
273601
773
0
$t
Springer Nature eBook
856
4 0
$u
https://doi.org/10.1007/978-3-030-76571-2
950
$a
Biomedical and Life Sciences (SpringerNature-11642)
筆 0 讀者評論
全部
電子館藏
館藏
1 筆 • 頁數 1 •
1
條碼號
館藏地
館藏流通類別
資料類型
索書號
使用類型
借閱狀態
預約狀態
備註欄
附件
000000199495
電子館藏
1圖書
電子書
EB QP623 .R627 2021 2021
一般使用(Normal)
在架
0
1 筆 • 頁數 1 •
1
多媒體
多媒體檔案
https://doi.org/10.1007/978-3-030-76571-2
評論
新增評論
分享你的心得
Export
取書館別
處理中
...
變更密碼
登入