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[ author_sort:"kisaalita, william ssempa, (1953-)" ]
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3D cell-based biosensors in drug dis...
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Kisaalita, William Ssempa, (1953-)
3D cell-based biosensors in drug discovery programsmicrotissue engineering for high throughput screening /
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
3D cell-based biosensors in drug discovery programsWilliam S. Kisaalita.
其他題名:
microtissue engineering for high throughput screening /
作者:
Kisaalita, William Ssempa,
出版者:
Boca Raton [Fla.] :CRC Press,2010.
面頁冊數:
466 p.
標題:
Biosensors.
電子資源:
Distributed by publisher. Purchase or institutional license may be required for access.
ISBN:
9781420073508 (e-book : PDF)
3D cell-based biosensors in drug discovery programsmicrotissue engineering for high throughput screening /
Kisaalita, William Ssempa,1953-
3D cell-based biosensors in drug discovery programs
microtissue engineering for high throughput screening /[electronic resource] :William S. Kisaalita. - Boca Raton [Fla.] :CRC Press,2010. - 466 p.
Includes bibliographical references and index.
(Publisher-supplied data) Biosensors and Bioassays -- Target-Driven Drug Discovery -- Comparative Genomics and Proteomics -- Comparative Structure and Function -- Chemical Microenvironmental Factors -- Spatial and Temporal Microenvironmental Factors -- Material Physical Property and Force Microenvironmental Factors -- Proteomics as a Promising Tool in the Search for 3D Biomarkers -- Readout Present and Near Future -- Ready-to-Use Commercial 3D Plates -- Challenges to Adopting 3D Cultures in HTS Programs -- Cases for 3D Cultures in Drug Discovery -- Ideal Case Study Design.
"This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.
Mode of access: World Wide Web.
ISBN: 9781420073508 (e-book : PDF)Subjects--Topical Terms:
188824
Biosensors.
Index Terms--Genre/Form:
214472
Electronic books.
3D cell-based biosensors in drug discovery programsmicrotissue engineering for high throughput screening /
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