國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁 到查詢結果 [ subject:"Physical chemistry." ]

切換: 標籤 | MARC模式 | ISBD

Carbon-oxygen bond activation throug...

Agrawal, Toolika.

Carbon-oxygen bond activation through iron catalysis.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Carbon-oxygen bond activation through iron catalysis.
作者:	Agrawal, Toolika.
面頁冊數:	118 p.
附註:	Source: Dissertation Abstracts International, Volume: 76-09(E), Section: B.
附註:	Adviser: Silas P. Cook.
Contained By:	Dissertation Abstracts International76-09B(E).
標題:	Organic chemistry.
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3702777
ISBN:	9781321742497

Carbon-oxygen bond activation through iron catalysis.
Agrawal, Toolika.

Carbon-oxygen bond activation through iron catalysis. - 118 p.

Source: Dissertation Abstracts International, Volume: 76-09(E), Section: B.

Thesis (Ph.D.)--Indiana University, 2015.

Transition metal-catalyzed cross-coupling reactions have emerged as the most sought after routes for carbon-carbon bond formation. A majority of these reactions utilize organic halides as coupling partners. These substrates are rarely available from natural sources, typically expensive and their use generates environmentally toxic halide waste. Phenols, alcohols and ketones are inexpensive and readily available from natural sources and their derivatives can be attractive substitutes for organic halides in cross-coupling reactions. Furthermore, expensive noble metals such as palladium are the catalysts of choice for most cross-coupling reactions. These metals are highly toxic and their use as catalysts for synthesis of active pharmaceutical ingredients (API) requires rigorous removal procedures, which adds to the cost of the final drug. Above all these noble metals are poor catalysts for activation of C-O bonds and hence, alternate catalyst systems are required. Herein we describe the development of inexpensive and environmentally benign iron catalysts for cross-coupling using C-O electrophiles in a move towards more environmentally friendly and sustainable cross-coupling technologies. More specifically iron-catalyzed coupling of both aryl sulfamates and tosylates with alkyl and aryl Grignard reagents and efforts towards coupling of unactivated alkyl tosylates and aryl Grignard reagents will be discussed.

ISBN: 9781321742497Subjects--Topical Terms:

708640
Organic chemistry.

Carbon-oxygen bond activation through iron catalysis.
LDR:02270nmm a2200277 4500 001 476069
005 20160418090148.5
008 160517s2015 ||||||||||||||||| ||eng d
020 $a 9781321742497
035 $a (MiAaPQ)AAI3702777
035 $a AAI3702777
040 $a MiAaPQ $c MiAaPQ
100 1 $a Agrawal, Toolika. $3 730327
245 1 0 $a Carbon-oxygen bond activation through iron catalysis.
300 $a 118 p.
500 $a Source: Dissertation Abstracts International, Volume: 76-09(E), Section: B.
500 $a Adviser: Silas P. Cook.
502 $a Thesis (Ph.D.)--Indiana University, 2015.
520 $a Transition metal-catalyzed cross-coupling reactions have emerged as the most sought after routes for carbon-carbon bond formation. A majority of these reactions utilize organic halides as coupling partners. These substrates are rarely available from natural sources, typically expensive and their use generates environmentally toxic halide waste. Phenols, alcohols and ketones are inexpensive and readily available from natural sources and their derivatives can be attractive substitutes for organic halides in cross-coupling reactions. Furthermore, expensive noble metals such as palladium are the catalysts of choice for most cross-coupling reactions. These metals are highly toxic and their use as catalysts for synthesis of active pharmaceutical ingredients (API) requires rigorous removal procedures, which adds to the cost of the final drug. Above all these noble metals are poor catalysts for activation of C-O bonds and hence, alternate catalyst systems are required. Herein we describe the development of inexpensive and environmentally benign iron catalysts for cross-coupling using C-O electrophiles in a move towards more environmentally friendly and sustainable cross-coupling technologies. More specifically iron-catalyzed coupling of both aryl sulfamates and tosylates with alkyl and aryl Grignard reagents and efforts towards coupling of unactivated alkyl tosylates and aryl Grignard reagents will be discussed.
590 $a School code: 0093.
650 4 $a Organic chemistry. $3 708640
650 4 $a Physical chemistry. $3 708580
690 $a 0490
690 $a 0494
710 2 $a Indiana University. $b Chemistry. $3 730328
773 0 $t Dissertation Abstracts International $g 76-09B(E).
790 $a 0093
791 $a Ph.D.
792 $a 2015
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3702777