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Homocysteine metabolism in health and disease

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Homocysteine metabolism in health and diseaseedited by Govind Prasad Dubey ... [et al.].
其他作者:	Dubey, Govind Prasad.
出版者:	Singapore :Springer Nature Singapore :2022.
面頁冊數:	xx, 276 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	HomocysteineMetabolism
電子資源:	https://doi.org/10.1007/978-981-16-6867-8
ISBN:	9789811668678$q(electronic bk.)

Homocysteine metabolism in health and disease
Homocysteine metabolism in health and disease[electronic resource] /edited by Govind Prasad Dubey ... [et al.]. - Singapore :Springer Nature Singapore :2022. - xx, 276 p. :ill., digital ;24 cm.

Module 1 -- Nutrition and Health -- Module 2_Disease -- Module 3_Advanced Research.

This book comprehensively reviews the association of homocysteine metabolism with the etiology of various human disorders. The well-defined chapters embedded the central and peripheral effects of homocysteine metabolism intricately related with cardiovascular, neurodegenerative, metabolic, and autoimmune disorders. Further, it discusses the mechanisms of perturbance of cellular proteostasis by elevated homocysteine levels and provides a comprehensive account of pathophysiological consequences and clinical implications of homocysteine-containing proteins. The book also reviews association of genetic variants of homocysteine metabolic genes with type 2 diabetes mellitus and obesity. It also describes the molecular mechanism of hyperhomocysteinemia in the negative/feedback regulation of neural stem cell proliferation and alterations in DNA methylation. Taken together, it summarizes the mechanisms of hyper homocysteinemia-induced endothelial dysfunction and physiological functions of hydrogen sulfide as the protective agent.

ISBN: 9789811668678$q(electronic bk.)

Standard No.: 10.1007/978-981-16-6867-8doiSubjects--Topical Terms:

921097
Homocysteine
--Metabolism

LC Class. No.: RC632.H65

Dewey Class. No.: 616.1071

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520 $a This book comprehensively reviews the association of homocysteine metabolism with the etiology of various human disorders. The well-defined chapters embedded the central and peripheral effects of homocysteine metabolism intricately related with cardiovascular, neurodegenerative, metabolic, and autoimmune disorders. Further, it discusses the mechanisms of perturbance of cellular proteostasis by elevated homocysteine levels and provides a comprehensive account of pathophysiological consequences and clinical implications of homocysteine-containing proteins. The book also reviews association of genetic variants of homocysteine metabolic genes with type 2 diabetes mellitus and obesity. It also describes the molecular mechanism of hyperhomocysteinemia in the negative/feedback regulation of neural stem cell proliferation and alterations in DNA methylation. Taken together, it summarizes the mechanisms of hyper homocysteinemia-induced endothelial dysfunction and physiological functions of hydrogen sulfide as the protective agent.
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