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Epigenetic technological applications

Zheng, Y. George.

Epigenetic technological applications

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Epigenetic technological applicationsedited by Y. George Zheng.
其他作者:	Zheng, Y. George.
出版者:	Amsterdam :Academic Press,c2015.
面頁冊數:	1 online resource (xxiii, 491 p., [18] p. of plates) :ill. (some col.)
標題:	EpigeneticsData processing.
電子資源:	click for full text
ISBN:	9780128010808 (electronic bk.)

Epigenetic technological applications
Epigenetic technological applications[electronic resource] /edited by Y. George Zheng. - Amsterdam :Academic Press,c2015. - 1 online resource (xxiii, 491 p., [18] p. of plates) :ill. (some col.) - Translational epigenetics series. - Translational epigenetics series..

Includes bibliographical references and index.

The state of the art of epigenetic technologies -- Technologies for the measurement and mapping of genomic 5-methylcytosine and 5-hydroxymethylcytosine -- High-throughput sequencing-based mapping of cytosine modifications -- Application of mass spectrometry in translational epigenetics -- Techniques analyzing chromatin modifications at specific single loci -- Comprehensive analysis of mammalian linker-histone variants and their mutants -- Crystallography-based mechanistic insights into epigenetic regulation -- Chemical and genetic approaches to study histone modifications -- Peptide microarrays for profiling of epigenetic targets -- Current methods for methylome profiling -- Bioinformatics and biostatistics in mining epigenetic disease markers and targets -- Computational modeling to elucidate molecular mechanisms of epigenetic memory -- DNA methyltransferase inhibitors for cancer therapy -- Histone acetyltransferases: enzymes, assays, and inhibitors -- In vitro histone deacetylase activity screening: making a case for better assays -- Enzymatic assays of histone methyltransferase enzymes -- Histone methyltransferase inhibitors for cancer therapy -- Discovery of histone demethylase inhibitors -- Histone demethylases: background, purification, and detection -- Animal model study of epigenetic inhibitors -- Index.

ISBN: 9780128010808 (electronic bk.)Subjects--Topical Terms:

752271
Epigenetics
--Data processing.

LC Class. No.: QH450 / .E6535 2015

Dewey Class. No.: 572.8/65

Epigenetic technological applications
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300 $a 1 online resource (xxiii, 491 p., [18] p. of plates) : $b ill. (some col.)
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504 $a Includes bibliographical references and index.
505 0 $a The state of the art of epigenetic technologies -- Technologies for the measurement and mapping of genomic 5-methylcytosine and 5-hydroxymethylcytosine -- High-throughput sequencing-based mapping of cytosine modifications -- Application of mass spectrometry in translational epigenetics -- Techniques analyzing chromatin modifications at specific single loci -- Comprehensive analysis of mammalian linker-histone variants and their mutants -- Crystallography-based mechanistic insights into epigenetic regulation -- Chemical and genetic approaches to study histone modifications -- Peptide microarrays for profiling of epigenetic targets -- Current methods for methylome profiling -- Bioinformatics and biostatistics in mining epigenetic disease markers and targets -- Computational modeling to elucidate molecular mechanisms of epigenetic memory -- DNA methyltransferase inhibitors for cancer therapy -- Histone acetyltransferases: enzymes, assays, and inhibitors -- In vitro histone deacetylase activity screening: making a case for better assays -- Enzymatic assays of histone methyltransferase enzymes -- Histone methyltransferase inhibitors for cancer therapy -- Discovery of histone demethylase inhibitors -- Histone demethylases: background, purification, and detection -- Animal model study of epigenetic inhibitors -- Index.
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650 0 $a Epigenetics $x Research $x Methodology. $3 752272
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700 1 $a Zheng, Y. George. $3 752270
830 0 $a Translational epigenetics series. $3 752178
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