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Foundations of comparative genomics

Mushegian, Arcady R.

Foundations of comparative genomics

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Foundations of comparative genomicsArcady R. Mushegian.
作者:	Mushegian, Arcady R.
出版者:	Amsterdam ;Academic Press,c2007.
面頁冊數:	ix, 265 p. :ill. ;27 cm.
標題:	Genomics.
電子資源:	An electronic book accessible through the World Wide Web; click for information
電子資源:	http://www.loc.gov/catdir/toc/ecip079/2007003418.html
電子資源:	http://www.loc.gov/catdir/enhancements/fy0707/2007003418-d.html
ISBN:	9780120887941

Foundations of comparative genomics
Mushegian, Arcady R.

Foundations of comparative genomics[electronic resource] /Arcady R. Mushegian. - Amsterdam ;Academic Press,c2007. - ix, 265 p. :ill. ;27 cm.

Includes bibliographical references (p. 238-257) and index.

The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology.

This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics. * Presents an historic overview of genome biology and its achievements * Includes topics not covered in other books such as minimal and ancestral genomes * Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level * Critically reviews horizontal gene transfer and other contentious issues * Covers comparative virology as a somewhat overlooked foundation of modern genome science.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2007.

Mode of access: World Wide Web.

ISBN: 9780120887941

Source: 112454:112542Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

209057
Genomics.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: QH447 / .M88 2007eb

Dewey Class. No.: 572.8/6

National Agricultural Library Call No.: QH447 / .M88 2007

National Library of Medicine Call No.: QU 58.5 / M987f 2007

Foundations of comparative genomics
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020 $a 9780120887941
020 $a 0120887940
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035 $a (OCoLC)162570604
035 $a ocn162570604
037 $a 112454:112542 $b Elsevier Science & Technology $n http://www.sciencedirect.com
040 $a OPELS $c OPELS
049 $a TEFA
050 1 4 $a QH447 $b .M88 2007eb
060 1 4 $a QU 58.5 $b M987f 2007
070 1 $a QH447 $b .M88 2007
082 0 4 $a 572.8/6 $2 22
100 1 $a Mushegian, Arcady R. $3 340579
245 1 0 $a Foundations of comparative genomics $h [electronic resource] / $c Arcady R. Mushegian.
260 $a Amsterdam ; $a Boston : $c c2007. $b Academic Press,
300 $a ix, 265 p. : $b ill. ; $c 27 cm.
504 $a Includes bibliographical references (p. 238-257) and index.
505 0 $a The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology.
520 $a This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics. * Presents an historic overview of genome biology and its achievements * Includes topics not covered in other books such as minimal and ancestral genomes * Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level * Critically reviews horizontal gene transfer and other contentious issues * Covers comparative virology as a somewhat overlooked foundation of modern genome science.
533 $a Electronic reproduction. $b Amsterdam : $c Elsevier Science & Technology, $d 2007. $n Mode of access: World Wide Web. $n System requirements: Web browser. $n Title from title screen (viewed on Aug. 2, 2007). $n Access may be restricted to users at subscribing institutions.
650 0 $a Genomics. $3 209057
650 0 $a Gene mapping. $3 196623
650 0 $a Physiology, Comparative. $3 229540
650 1 2 $a Genomics $x methods. $3 224200
650 2 2 $a Genetic Techniques. $3 196466
650 2 2 $a Sequence Analysis $x methods. $3 197533
655 7 $a Electronic books. $2 local. $3 214472
710 2 $a ScienceDirect (Online service) $3 307425
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780120887941 $z An electronic book accessible through the World Wide Web; click for information
856 4 1 $3 Table of contents only $u http://www.loc.gov/catdir/toc/ecip079/2007003418.html
856 4 2 $3 Publisher description $u http://www.loc.gov/catdir/enhancements/fy0707/2007003418-d.html
994 $a C0 $b TEF

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http://www.sciencedirect.com/science/book/9780120887941
http://www.loc.gov/catdir/toc/ecip079/2007003418.html
http://www.loc.gov/catdir/enhancements/fy0707/2007003418-d.html

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