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Molecular basis for mitochondrial si...

Rostovtseva, Tatiana K.

Molecular basis for mitochondrial signaling

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Molecular basis for mitochondrial signalingedited by Tatiana K. Rostovtseva.
其他作者:	Rostovtseva, Tatiana K.
出版者:	Cham :Springer International Publishing :2017.
面頁冊數:	xiv, 386 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Mitochondria.
電子資源:	http://dx.doi.org/10.1007/978-3-319-55539-3
ISBN:	9783319555393$q(electronic bk.)

Molecular basis for mitochondrial signaling
Molecular basis for mitochondrial signaling[electronic resource] /edited by Tatiana K. Rostovtseva. - Cham :Springer International Publishing :2017. - xiv, 386 p. :ill., digital ;24 cm. - Biological and medical physics, biomedical engineering,1618-7210. - Biological and medical physics, biomedical engineering..

From the Contents: Mitochondrial Calcium Signaling -- Systems approaches to mitochondrial calcium signaling -- The mitochondrial Calcium Uniporter: Molecular Composition And Physiological Role -- Molecular Mechanisms of Mitochondrial Ca2+ Uptake -- Ca2+ uniporter and male fertility.

This book covers recent advances in the study of structure, function, and regulation of metabolite, protein and ion translocating channels, and transporters in mitochondria. A wide array of cutting-edge methods are covered, ranging from electrophysiology and cell biology to bioinformatics, as well as structural, systems, and computational biology. At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established. After years of work on the physiology and structure of VDAC channels in the mitochondrial outer membrane, there have been multiple discoveries on VDAC permeation and regulation by cytosolic proteins. Recent breakthroughs in structural studies of the mitochondrial cholesterol translocator reveal a set of novel unexpected features and provide essential clues for defining therapeutic strategies. Molecular Basis for Mitochondrial Signaling covers these and many more recent studies of mitochondria function, their communication with other organelles, and their critical roles in development, aging, and in a plethora of stressful or degenerative events. Authored by leading researchers in the field, this volume will be an indispensable reference resource for graduate students and academics working in related areas of biophysics and cell biology as well as for professionals within industry.

ISBN: 9783319555393$q(electronic bk.)

Standard No.: 10.1007/978-3-319-55539-3doiSubjects--Topical Terms:

265367
Mitochondria.

LC Class. No.: QH603.M5

Dewey Class. No.: 571.657

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520 $a This book covers recent advances in the study of structure, function, and regulation of metabolite, protein and ion translocating channels, and transporters in mitochondria. A wide array of cutting-edge methods are covered, ranging from electrophysiology and cell biology to bioinformatics, as well as structural, systems, and computational biology. At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established. After years of work on the physiology and structure of VDAC channels in the mitochondrial outer membrane, there have been multiple discoveries on VDAC permeation and regulation by cytosolic proteins. Recent breakthroughs in structural studies of the mitochondrial cholesterol translocator reveal a set of novel unexpected features and provide essential clues for defining therapeutic strategies. Molecular Basis for Mitochondrial Signaling covers these and many more recent studies of mitochondria function, their communication with other organelles, and their critical roles in development, aging, and in a plethora of stressful or degenerative events. Authored by leading researchers in the field, this volume will be an indispensable reference resource for graduate students and academics working in related areas of biophysics and cell biology as well as for professionals within industry.
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