國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁 到查詢結果 [ subject:"Protein-Ligand Interactions." ]

切換: 標籤 | MARC模式 | ISBD

Peptides and peptide-based biomateri...

Bergquist, Peter L.

Peptides and peptide-based biomaterials and their biomedical applications

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Peptides and peptide-based biomaterials and their biomedical applicationsedited by Anwar Sunna, Andrew Care, Peter L. Bergquist.
其他作者:	Sunna, Anwar.
出版者:	Cham :Springer International Publishing :2017.
面頁冊數:	xiii, 300 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
標題:	PeptidesBiotechnology.
電子資源:	http://dx.doi.org/10.1007/978-3-319-66095-0
ISBN:	9783319660950$q(electronic bk.)

Peptides and peptide-based biomaterials and their biomedical applications
Peptides and peptide-based biomaterials and their biomedical applications[electronic resource] /edited by Anwar Sunna, Andrew Care, Peter L. Bergquist. - Cham :Springer International Publishing :2017. - xiii, 300 p. :ill. (some col.), digital ;24 cm. - Advances in experimental medicine and biology,v.10300065-2598 ;. - Advances in experimental medicine and biology ;946..

This edited volume is composed of chapters written by experts in the field describing fundamental research on small peptide fragments in relation to their biological action and potential roles in biomedical applications from diagnosis to implant protection. It provides a review of the wide scope and significance of these relatively simple arrays of amino acids that have the ability to bind to surfaces of all kinds and can facilitate the autonomous assembly of structures in nanotechnology as well as penetrating cell membranes and delivering therapeutic drugs. Readers will learn of some of the impediments to a wider and more comprehensive catalog of these molecules and of some of the attributes of rationally-designed and chemically synthesised peptides as anticancer agents. An overview is provided of the expansive variety of biological leads for biomedically relevant peptides as well as the wide array of tissues and biological, bioactive scaffolds that are dependent on these short peptide sequences addressing topics such as cartilage and hard tissue initiation and regeneration and the transition of active reagents from molluscs to drug leads for the treatment of chronic pain. Peptides can possess surface-specific non-covalent adsorption properties that can be exploited to enhance the functionality of medical implant materials but their implementation is largely on a trial-and-error basis because an understanding of general structure/function relationships is lacking. Molecular simulation approaches can provide relevant details at the atomic scale and prospects for advancing peptide-mediated medical implant surface treatments via molecular simulation are summarized. The literature has papers emphasizing the role of peptides in the design of biohybrid functional surfaces and there has been a growing interest in applying peptides as materials-selective assemblers and self-organizers, but applications are based largely on an empirical understanding of solid surface binding characteristics, as reviewed here. The present work is written for researchers who may be considering entering this field and are exposed to a mass of fundamental research information on individual applications. It has been our intention to trace how and where the research has emerged and to outline the opportunities we see to develop novel and well-grounded tools for specific therapeutic scenarios.

ISBN: 9783319660950$q(electronic bk.)

Standard No.: 10.1007/978-3-319-66095-0doiSubjects--Topical Terms:

220382
Peptides
--Biotechnology.

LC Class. No.: QP552.P4

Dewey Class. No.: 572.65

Peptides and peptide-based biomaterials and their biomedical applications
LDR:03542nmm a2200337 a 4500 001 523276
003 DE-He213
005 20180419132007.0
006 m d
007 cr nn 008maaau
008 180628s2017 gw s 0 eng d
020 $a 9783319660950$q(electronic bk.)
020 $a 9783319660943$q(paper)
024 7 $a 10.1007/978-3-319-66095-0 $2 doi
035 $a 978-3-319-66095-0
040 $a GP $c GP
041 0 $a eng
050 4 $a QP552.P4
072 7 $a MBGR $2 bicssc
072 7 $a PSD $2 bicssc
072 7 $a SCI049000 $2 bisacsh
072 7 $a MED067000 $2 bisacsh
082 0 4 $a 572.65 $2 23
090 $a QP552.P4 $b P424 2017
245 0 0 $a Peptides and peptide-based biomaterials and their biomedical applications $h [electronic resource] / $c edited by Anwar Sunna, Andrew Care, Peter L. Bergquist.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2017.
300 $a xiii, 300 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.1030
520 $a This edited volume is composed of chapters written by experts in the field describing fundamental research on small peptide fragments in relation to their biological action and potential roles in biomedical applications from diagnosis to implant protection. It provides a review of the wide scope and significance of these relatively simple arrays of amino acids that have the ability to bind to surfaces of all kinds and can facilitate the autonomous assembly of structures in nanotechnology as well as penetrating cell membranes and delivering therapeutic drugs. Readers will learn of some of the impediments to a wider and more comprehensive catalog of these molecules and of some of the attributes of rationally-designed and chemically synthesised peptides as anticancer agents. An overview is provided of the expansive variety of biological leads for biomedically relevant peptides as well as the wide array of tissues and biological, bioactive scaffolds that are dependent on these short peptide sequences addressing topics such as cartilage and hard tissue initiation and regeneration and the transition of active reagents from molluscs to drug leads for the treatment of chronic pain. Peptides can possess surface-specific non-covalent adsorption properties that can be exploited to enhance the functionality of medical implant materials but their implementation is largely on a trial-and-error basis because an understanding of general structure/function relationships is lacking. Molecular simulation approaches can provide relevant details at the atomic scale and prospects for advancing peptide-mediated medical implant surface treatments via molecular simulation are summarized. The literature has papers emphasizing the role of peptides in the design of biohybrid functional surfaces and there has been a growing interest in applying peptides as materials-selective assemblers and self-organizers, but applications are based largely on an empirical understanding of solid surface binding characteristics, as reviewed here. The present work is written for researchers who may be considering entering this field and are exposed to a mass of fundamental research information on individual applications. It has been our intention to trace how and where the research has emerged and to outline the opportunities we see to develop novel and well-grounded tools for specific therapeutic scenarios.
650 0 $a Peptides $x Biotechnology. $3 220382
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Molecular Medicine. $3 273932
650 2 4 $a Protein-Ligand Interactions. $3 348845
650 2 4 $a Biomaterials. $3 274415
700 1 $a Sunna, Anwar. $3 794380
700 1 $a Care, Andrew. $3 794381
700 1 $a Bergquist, Peter L. $3 794382
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a Advances in experimental medicine and biology ; $v 946. $3 557559
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-66095-0
950 $a Biomedical and Life Sciences (Springer-11642)