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Eukaryotic transcription factors

Latchman, David S.

Eukaryotic transcription factors

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Eukaryotic transcription factorsDavid S. Latchman.
作者:	Latchman, David S.
出版者:	Amsterdam ;Elsevier/Academic Press,2008.
面頁冊數:	xxviii, 471 p. :ill. (some col.) ;26 cm.
標題:	Transcription factors.
電子資源:	An electronic book accessible through the World Wide Web; click for information
ISBN:	9780123739834

Eukaryotic transcription factors
Latchman, David S.

Eukaryotic transcription factors[electronic resource] /David S. Latchman. - 5th ed. - Amsterdam ;Elsevier/Academic Press,2008. - xxviii, 471 p. :ill. (some col.) ;26 cm.

Includes bibliographical references and index.

DNA sequences, transcription factors and chromatin structure; Methods for studying transcription factors; RNA polymerases and the basal transcriptional complex; Families of DNA binding transcription factors; Activation of gene expression by transcription factors; Repression of gene expression by transcription factors; Regulation of transcription factor synthesis; Regulation of transcription factor activity; Transcription factors and human disease.

Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Brand new coverage in this edition includes: * Potential of transcription factors as therapeutic targets in human disease * Importance of histone modifications * Use of genome-based sequence analysis and high-throughput methods * Applications of the chromatin immunoprecipitation (ChIP) assay * Transcriptional elongation * Regulation by post-translational modifications * Regulatory networks and bioinformatics.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2008.

Mode of access: World Wide Web.

ISBN: 9780123739834

Source: 137678:137815Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

202406
Transcription factors.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: QP552.T68 / L38 2008eb

Dewey Class. No.: 572.8/845

National Agricultural Library Call No.: QP552.T68 / L38 2008

National Library of Medicine Call No.: 2008 A-369

Eukaryotic transcription factors
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520 $a Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Brand new coverage in this edition includes: * Potential of transcription factors as therapeutic targets in human disease * Importance of histone modifications * Use of genome-based sequence analysis and high-throughput methods * Applications of the chromatin immunoprecipitation (ChIP) assay * Transcriptional elongation * Regulation by post-translational modifications * Regulatory networks and bioinformatics.
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