國立高雄大學圖資館 |

登入

回首頁

Histopathology of preclinical toxicity studiesinterpretation and relevance in drug safety evaluation /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Histopathology of preclinical toxicity studiesPeter Greaves.
其他題名:	interpretation and relevance in drug safety evaluation /
作者:	Greaves, P.
出版者:	Amsterdam ;Academic Press,2007.
面頁冊數:	1 online resource (vii, 953 p.) :col. ill.
標題:	DrugsToxicity testing.
電子資源:	http://www.sciencedirect.com/science/book/9780444527714
ISBN:	9780444527714

Histopathology of preclinical toxicity studiesinterpretation and relevance in drug safety evaluation /
Greaves, P.M.B., Ch.B.

Histopathology of preclinical toxicity studiesinterpretation and relevance in drug safety evaluation /[electronic resource] :Peter Greaves. - 3rd ed. - Amsterdam ;Academic Press,2007. - 1 online resource (vii, 953 p.) :col. ill.

Includes bibliographical references and index.

Introduction -- Integumentary System -- Mammary Gland -- Haemopoietic and Lymphatic Systems -- Musculoskeletal System -- Respiratory Tract -- Cardiovascular System -- Gastrointestinal tract.

This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology. NEW TO THE THIRD EDITION: * Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies * General comments to each chapter about the relevance of pathological findings to humans * Provides essential information that can help decide the relevance of particular lesions for patients.

ISBN: 9780444527714

Source: 133525:133650Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

571194
Drugs
--Toxicity testing.Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: RA1238 / .G74 2007

Dewey Class. No.: 615.9

National Library of Medicine Call No.: 2007 F-019

Histopathology of preclinical toxicity studiesinterpretation and relevance in drug safety evaluation /
LDR:03105cmm 2200421Ia 4500 001 342435
005 20120813090238.0
006 m d
007 cr cn|||||||||
008 120925s2007 ne a ob 001 0 eng d
019 $a 123422455 $a 154703074 $a 648163839
020 $a 9780444527714
020 $a 0444527710
020 $a 9780080471303 (electronic bk.)
020 $a 0080471307 (electronic bk.)
029 1 $a NZ1 $b 11778301
029 1 $a DEBBG $b BV039835234
035 $a ocn162131441
037 $a 133525:133650 $b Elsevier Science & Technology $n http://www.sciencedirect.com
040 $a OPELS $b eng $c OPELS $d BAKER $d OPELS $d OCLCG $d OCLCQ $d N$T $d YDXCP $d TEX $d IDEBK $d E7B $d OCLCQ
049 $a NTYA
050 4 $a RA1238 $b .G74 2007
060 4 $a 2007 F-019
060 4 $a QV 771 $b G787h 2007
072 7 $a MED $x 071000 $2 bisacsh
082 0 4 $a 615.9 $2 22
100 1 $a Greaves, P. $q (Peter) $c M.B., Ch.B. $3 571193
245 1 0 $a Histopathology of preclinical toxicity studies $h [electronic resource] : $b interpretation and relevance in drug safety evaluation / $c Peter Greaves.
250 $a 3rd ed.
260 $a Amsterdam ; $a New York : $b Academic Press, $c 2007.
300 $a 1 online resource (vii, 953 p.) : $b col. ill.
504 $a Includes bibliographical references and index.
505 0 $a Introduction -- Integumentary System -- Mammary Gland -- Haemopoietic and Lymphatic Systems -- Musculoskeletal System -- Respiratory Tract -- Cardiovascular System -- Gastrointestinal tract.
520 $a This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology. NEW TO THE THIRD EDITION: * Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies * General comments to each chapter about the relevance of pathological findings to humans * Provides essential information that can help decide the relevance of particular lesions for patients.
588 $a Description based on print version record.
650 0 $a Drugs $x Toxicity testing. $3 571194
650 0 $a Laboratory animals $x Histopathology. $3 571195
650 1 2 $a Drug Evaluation, Preclinical. $3 226663
650 2 2 $a Animals, Laboratory. $3 265347
650 2 2 $a Histology. $3 188731
650 2 2 $a Pathology. $3 196513
650 7 $a MEDICAL $x Pharmacology. $2 bisacsh $3 504870
655 4 $a Electronic books. $2 local. $3 214472
776 0 8 $i Print version: $a Greaves, P. (Peter) M.B., Ch. B. $t Histopathology of preclinical toxicity studies. $b 3rd ed. $d Amsterdam ; New York : Academic Press, 2007 $z 9780444527714 $z 0444527710 $w (OCoLC)123373759
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780444527714
938 $a Baker & Taylor $b BKTY $c 159.00 $d .00 $i 0444527710 $n 0007045425 $s active
938 $a YBP Library Services $b YANK $n 2551346
938 $a ebrary $b EBRY $n ebr10506459