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The MIF handbook

Bucala, Richard.

The MIF handbook

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The MIF handbookedited by Richard Bucala.
其他作者:	Bucala, Richard.
出版者:	Singapore ;World Scientific,c2012.
面頁冊數:	1 online resource (viii, 390 p.) :ill.
標題:	Cytokines.
電子資源:	http://www.worldscientific.com/worldscibooks/10.1142/8032#t=toc
ISBN:	9789814335362 (electronic bk.)

The MIF handbook
The MIF handbook[electronic resource] /edited by Richard Bucala. - Singapore ;World Scientific,c2012. - 1 online resource (viii, 390 p.) :ill.

Includes bibliographical references and index.

The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.

ISBN: 9789814335362 (electronic bk.)Subjects--Topical Terms:

195178
Cytokines.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: QP552.M54 / .M54 2012eb

Dewey Class. No.: 572/.696

The MIF handbook
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245 0 4 $a The MIF handbook $h [electronic resource] / $c edited by Richard Bucala.
260 $a Singapore ; $a Hackensack, NJ. : $b World Scientific, $c c2012.
300 $a 1 online resource (viii, 390 p.) : $b ill.
504 $a Includes bibliographical references and index.
520 $a The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.
588 $a Description based on print version record.
650 0 $a Cytokines. $3 195178
650 0 $a Immune response $x Regulation. $3 192822
655 4 $a Electronic books. $2 local. $3 214472
700 1 $a Bucala, Richard. $3 575840
856 4 0 $u http://www.worldscientific.com/worldscibooks/10.1142/8032#t=toc