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A guide to numerical modelling in sy...

Deuflhard, P.

A guide to numerical modelling in systems biology /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	A guide to numerical modelling in systems biology /Peter Deuflhard, Susanna Röblitz.
作者:	Deuflhard, P.
其他作者:	Röblitz, Susanna.
出版者:	Cham :Springer,c2015.
面頁冊數:	x, 168 p. :ill. (some col.) ;24 cm.
標題:	Systems biologyMathematical models.
ISBN:	9783319200583 (hbk.) :

A guide to numerical modelling in systems biology /
Deuflhard, P.

A guide to numerical modelling in systems biology /Peter Deuflhard, Susanna Röblitz. - Cham :Springer,c2015. - x, 168 p. :ill. (some col.) ;24 cm. - Texts in computational science and engineering,121611-0994 ;. - Texts in computational science and engineering ;6..

Includes bibliographical references and index.

Preface -- Outline -- ODE Models for Systems Biological Networks -- Numerical Simulation of ODE Models -- Parameter Identification in ODE Models -- Appendix -- Software -- Index.

This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for computational biologists. The authors of the present book have worked hard to fill this gap. The result is not a book on systems biology, but on computational methods in systems biology. This book originated from courses taught by the authors at Freie Universität Berlin. The guiding idea of the courses was to convey those mathematical insights that are indispensable for systems biology, teaching the necessary mathematical prerequisites by means of many illustrative examples and without any theorems. The three chapters cover the mathematical modelling of biochemical and physiological processes, numerical simulation of the dynamics of biological networks, and identification of model parameters by means of comparisons with real data. Throughout the text, the strengths and weaknesses of numerical algorithms with respect to various systems biological issues are discussed. Web addresses for downloading the corresponding software are also included.

ISBN: 9783319200583 (hbk.) :NT$1229Subjects--Topical Terms:

609539
Systems biology
--Mathematical models.

LC Class. No.: QH323.5

Dewey Class. No.: 570.1/5118

A guide to numerical modelling in systems biology /
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245 1 2 $a A guide to numerical modelling in systems biology / $c Peter Deuflhard, Susanna Röblitz.
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300 $a x, 168 p. : $b ill. (some col.) ; $c 24 cm.
490 1 $a Texts in computational science and engineering, $x 1611-0994 ; $v 12
504 $a Includes bibliographical references and index.
505 0 $a Preface -- Outline -- ODE Models for Systems Biological Networks -- Numerical Simulation of ODE Models -- Parameter Identification in ODE Models -- Appendix -- Software -- Index.
520 $a This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for computational biologists. The authors of the present book have worked hard to fill this gap. The result is not a book on systems biology, but on computational methods in systems biology. This book originated from courses taught by the authors at Freie Universität Berlin. The guiding idea of the courses was to convey those mathematical insights that are indispensable for systems biology, teaching the necessary mathematical prerequisites by means of many illustrative examples and without any theorems. The three chapters cover the mathematical modelling of biochemical and physiological processes, numerical simulation of the dynamics of biological networks, and identification of model parameters by means of comparisons with real data. Throughout the text, the strengths and weaknesses of numerical algorithms with respect to various systems biological issues are discussed. Web addresses for downloading the corresponding software are also included.
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650 0 $a Bioinformatics. $3 194415
650 0 $a Differential equations. $3 183925
700 1 $a Röblitz, Susanna. $3 709138
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