國立高雄大學圖資館 |

Metabonomics and gut microbiota in nutrition and disease

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Metabonomics and gut microbiota in nutrition and diseaseedited by Sunil Kochhar, Francois-Pierre Martin.
其他作者:	Kochhar, Sunil.
出版者:	London :Springer London :2015.
面頁冊數:	xvi, 375 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
標題:	Digestive organsMicrobiology.
電子資源:	http://dx.doi.org/10.1007/978-1-4471-6539-2
ISBN:	9781447165392 (electronic bk.)

Metabonomics and gut microbiota in nutrition and disease
Metabonomics and gut microbiota in nutrition and disease[electronic resource] /edited by Sunil Kochhar, Francois-Pierre Martin. - London :Springer London :2015. - xvi, 375 p. :ill. (some col.), digital ;24 cm. - Molecular and integrative toxicology,2168-4219. - Molecular and integrative toxicology..

Introduction to Metabolomics in systems biology research -- Metabolomics in clinical practice.-Adopting multivariate non-parametric tools to determine genotype-phenotype interactions in health and disease -- Metabolomics in Translational Research for Personalized Medicine and Nutrition -- Can we use Metabolomics to Understand Changes to Gut Microbiota Populations and Function A Nutritional Perspective -- Automated annotation of microbial and human flavonoid derived metabolites -- Metabonomics in neonatal and paediatric research: Studying and modulating gut functional ecology for optimal growth and development -- Metabolomics and Milk: the Development of the Microbiota in Breast Fed Infants -- Metabonomics and gut microbial paradigm in healthy ageing -- Roles of herbal medicine in modulating gut microbiota associated with health and diseases -- Gut microbiota and metabolic diseases: from pathogenesis to therapeutic perspective -- Role of microbiota in regulating host lipid metabolism and disease risk -- Role of the Gut Microbiota in Maintaining GI Health: Highlights on Inflammatory Bowel Disease -- Deciphering the gut microbial contribution to the aetiology of autism development -- The Modulation of Drug Efficacy and Toxicity by the Gut Microbiome -- Understanding the benefits of bariatric surgery on gut physiology: implications for obesity, type 2 diabetes and cardiovascular disease.

This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also examines the translatability of systems biology approaches into applied clinical research and to patient health and nutrition. The rise in multifactorial disorders, the lack of understanding of the molecular processes at play and the needs for disease prediction in asymptomatic conditions are some of the many questions that system biology approaches are well suited to address. Achieving this goal lies in our ability to model and understand the complex web of interactions between genetics, metabolism, environmental factors, and gut microbiota. Being the most densely populated microbial ecosystem on earth, gut microbiota co-evolved as a key component of human biology, essentially extending the physiological definition of humans. Major advances in microbiome research have shown that the contribution of the intestinal microbiota to the overall health status of the host has been so far underestimated. Human host gut microbial interaction is one of the most significant human health considerations of the present day with relevance for both prevention of disease via microbiota-oriented environmental protection as well as strategies for new therapeutic approaches using microbiota as targets and/or biomarkers. In many aspects, humans are not a complete and fully healthy organism without their appropriate microbiological components. Increasingly, scientific evidence identifies gut microbiota as a key biological interface between human genetics and environmental conditions encompassing nutrition. Microbiota dysbiosis or variation in metabolic activity has been associated with metabolic deregulation (e.g. obesity, inflammatory bowel disease), disease risk factor (e.g. coronary heart disease) and even the aetiology of various pathologies (e.g. autism, cancer), although causal role into impaired metabolism still needs to be established. Metabonomics and Gut Microbiota in Nutrition and Disease serves as a handbook for postgraduate students, researchers in life sciences or health sciences, scientists in academic and industrial environments working in application areas as diverse as health, disease, nutrition, microbial research and human clinical medicine.

ISBN: 9781447165392 (electronic bk.)

Standard No.: 10.1007/978-1-4471-6539-2doiSubjects--Topical Terms:

711031
Digestive organs
--Microbiology.

LC Class. No.: QR171

Dewey Class. No.: 612.3

Metabonomics and gut microbiota in nutrition and disease
LDR:05021nmm a2200325 a 4500 001 459951
003 DE-He213
005 20150609114855.0
006 m d
007 cr nn 008maaau
008 151110s2015 enk s 0 eng d
020 $a 9781447165392 (electronic bk.)
020 $a 9781447165385 (paper)
024 7 $a 10.1007/978-1-4471-6539-2 $2 doi
035 $a 978-1-4471-6539-2
040 $a GP $c GP
041 0 $a eng
050 4 $a QR171
072 7 $a MMG $2 bicssc
072 7 $a MED071000 $2 bisacsh
082 0 4 $a 612.3 $2 23
090 $a QR171 $b .M587 2015
245 0 0 $a Metabonomics and gut microbiota in nutrition and disease $h [electronic resource] / $c edited by Sunil Kochhar, Francois-Pierre Martin.
260 $a London : $b Springer London : $b Imprint: Springer, $c 2015.
300 $a xvi, 375 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Molecular and integrative toxicology, $x 2168-4219
505 0 $a Introduction to Metabolomics in systems biology research -- Metabolomics in clinical practice.-Adopting multivariate non-parametric tools to determine genotype-phenotype interactions in health and disease -- Metabolomics in Translational Research for Personalized Medicine and Nutrition -- Can we use Metabolomics to Understand Changes to Gut Microbiota Populations and Function A Nutritional Perspective -- Automated annotation of microbial and human flavonoid derived metabolites -- Metabonomics in neonatal and paediatric research: Studying and modulating gut functional ecology for optimal growth and development -- Metabolomics and Milk: the Development of the Microbiota in Breast Fed Infants -- Metabonomics and gut microbial paradigm in healthy ageing -- Roles of herbal medicine in modulating gut microbiota associated with health and diseases -- Gut microbiota and metabolic diseases: from pathogenesis to therapeutic perspective -- Role of microbiota in regulating host lipid metabolism and disease risk -- Role of the Gut Microbiota in Maintaining GI Health: Highlights on Inflammatory Bowel Disease -- Deciphering the gut microbial contribution to the aetiology of autism development -- The Modulation of Drug Efficacy and Toxicity by the Gut Microbiome -- Understanding the benefits of bariatric surgery on gut physiology: implications for obesity, type 2 diabetes and cardiovascular disease.
520 $a This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also examines the translatability of systems biology approaches into applied clinical research and to patient health and nutrition. The rise in multifactorial disorders, the lack of understanding of the molecular processes at play and the needs for disease prediction in asymptomatic conditions are some of the many questions that system biology approaches are well suited to address. Achieving this goal lies in our ability to model and understand the complex web of interactions between genetics, metabolism, environmental factors, and gut microbiota. Being the most densely populated microbial ecosystem on earth, gut microbiota co-evolved as a key component of human biology, essentially extending the physiological definition of humans. Major advances in microbiome research have shown that the contribution of the intestinal microbiota to the overall health status of the host has been so far underestimated. Human host gut microbial interaction is one of the most significant human health considerations of the present day with relevance for both prevention of disease via microbiota-oriented environmental protection as well as strategies for new therapeutic approaches using microbiota as targets and/or biomarkers. In many aspects, humans are not a complete and fully healthy organism without their appropriate microbiological components. Increasingly, scientific evidence identifies gut microbiota as a key biological interface between human genetics and environmental conditions encompassing nutrition. Microbiota dysbiosis or variation in metabolic activity has been associated with metabolic deregulation (e.g. obesity, inflammatory bowel disease), disease risk factor (e.g. coronary heart disease) and even the aetiology of various pathologies (e.g. autism, cancer), although causal role into impaired metabolism still needs to be established. Metabonomics and Gut Microbiota in Nutrition and Disease serves as a handbook for postgraduate students, researchers in life sciences or health sciences, scientists in academic and industrial environments working in application areas as diverse as health, disease, nutrition, microbial research and human clinical medicine.
650 0 $a Digestive organs $x Microbiology. $3 711031
650 0 $a Systems biology. $3 282663
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Pharmacology/Toxicology. $3 273652
650 2 4 $a Medical Microbiology. $3 273931
650 2 4 $a Food Science. $3 274110
650 2 4 $a Nutrition. $3 192796
700 1 $a Kochhar, Sunil. $3 711029
700 1 $a Martin, Francois-Pierre. $3 711030
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a Molecular and integrative toxicology. $3 567050
856 4 0 $u http://dx.doi.org/10.1007/978-1-4471-6539-2
950 $a Biomedical and Life Sciences (Springer-11642)