國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Myeloid-derived suppressor cells and...

Escors, David.

Myeloid-derived suppressor cells and cancer

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Myeloid-derived suppressor cells and cancerby David Escors ... [et al.].
其他作者:	Escors, David.
出版者:	Cham :Springer International Publishing :2016.
面頁冊數:	ix, 102 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Suppressor cells.
電子資源:	http://dx.doi.org/10.1007/978-3-319-26821-7
ISBN:	9783319268217$q(electronic bk.)

Myeloid-derived suppressor cells and cancer
Myeloid-derived suppressor cells and cancer[electronic resource] /by David Escors ... [et al.]. - Cham :Springer International Publishing :2016. - ix, 102 p. :ill., digital ;24 cm. - SpringerBriefs in immunology,2194-2773. - SpringerBriefs in immunology..

Controversies in Neoplastic Myeloplasia -- Differentiation of Murine Myeloid-derived Suppressor Cells -- Human MDSCs -- Ex Vivo MDSC Differentiation Models -- Immunoregulatory myeloid cells in the tumor microenvironment -- Signal Transducer and Activation of Transcription 3: A Master Regulator of Myeloid-derived Suppressor Cells -- Future Perspectives.

The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs. These cells are distributed systemically, resulting in general immunosuppression. They also infiltrate tumours, promoting their progression and metastasis by inhibiting the natural anti-tumour immune response. As these cells also interact with classical anti-neoplastic treatments, they have become major therapeutic targets in the pharmaceutical industry and in oncology research.

ISBN: 9783319268217$q(electronic bk.)

Standard No.: 10.1007/978-3-319-26821-7doiSubjects--Topical Terms:

741628
Suppressor cells.

LC Class. No.: QR185.8.S96

Dewey Class. No.: 616.079

Myeloid-derived suppressor cells and cancer
LDR:02226nmm a2200325 a 4500 001 483712
003 DE-He213
005 20160908163704.0
006 m d
007 cr nn 008maaau
008 161012s2016 gw s 0 eng d
020 $a 9783319268217$q(electronic bk.)
020 $a 9783319268194$q(paper)
024 7 $a 10.1007/978-3-319-26821-7 $2 doi
035 $a 978-3-319-26821-7
040 $a GP $c GP
041 0 $a eng
050 4 $a QR185.8.S96
072 7 $a MJCM $2 bicssc
072 7 $a MED044000 $2 bisacsh
082 0 4 $a 616.079 $2 23
090 $a QR185.8.S96 $b M996 2016
245 0 0 $a Myeloid-derived suppressor cells and cancer $h [electronic resource] / $c by David Escors ... [et al.].
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a ix, 102 p. : $b ill., digital ; $c 24 cm.
490 1 $a SpringerBriefs in immunology, $x 2194-2773
505 0 $a Controversies in Neoplastic Myeloplasia -- Differentiation of Murine Myeloid-derived Suppressor Cells -- Human MDSCs -- Ex Vivo MDSC Differentiation Models -- Immunoregulatory myeloid cells in the tumor microenvironment -- Signal Transducer and Activation of Transcription 3: A Master Regulator of Myeloid-derived Suppressor Cells -- Future Perspectives.
520 $a The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells, inflammatory macrophages and granulocytes), there is an increase in highly immature MDSCs. These cells are distributed systemically, resulting in general immunosuppression. They also infiltrate tumours, promoting their progression and metastasis by inhibiting the natural anti-tumour immune response. As these cells also interact with classical anti-neoplastic treatments, they have become major therapeutic targets in the pharmaceutical industry and in oncology research.
650 0 $a Suppressor cells. $3 741628
650 0 $a T cells. $3 224601
650 0 $a Cancer $x Immunotherapy. $3 201873
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Immunology. $3 189152
650 2 4 $a Cancer Research. $3 273660
650 2 4 $a Oncology. $3 195181
650 2 4 $a Cell Biology. $3 274165
700 1 $a Escors, David. $3 560845
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a SpringerBriefs in immunology. $3 712773
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-26821-7
950 $a Biomedical and Life Sciences (Springer-11642)