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Translational anatomy and cell biolo...

Boeckers, Tobias M.

Translational anatomy and cell biology of Autism spectrum disorder

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Translational anatomy and cell biology of Autism spectrum disorderedited by Michael J. Schmeisser, Tobias M. Boeckers.
其他作者:	Schmeisser, Michael J.
出版者:	Cham :Springer International Publishing :2017.
面頁冊數:	viii, 211 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Autism spectrum disordersMolecular aspects.
電子資源:	http://dx.doi.org/10.1007/978-3-319-52498-6
ISBN:	9783319524986$q(electronic bk.)

Translational anatomy and cell biology of Autism spectrum disorder
Translational anatomy and cell biology of Autism spectrum disorder[electronic resource] /edited by Michael J. Schmeisser, Tobias M. Boeckers. - Cham :Springer International Publishing :2017. - viii, 211 p. :ill., digital ;24 cm. - Advances in anatomy, embryology and cell biology,2240301-5556 ;. - Advances in anatomy, embryology and cell biology ;211..

Anatomy and cell biology of autism spectrum disorder: Lessons from human genetics -- Neuroanatomy and neuropathology of autism spectrum disorder in humans -- Modelling autistic neurons with induced pluripotent stem cells -- Modelling autistic features in mice using quantitative genetic approaches -- Behavioural phenotypes and neural circuit dysfunctions in mouse models of autism spectrum disorder -- Cerebellar and striatal pathologies in mouse models of autism spectrum disorder -- The role of neurotrophic factors in mouse models of autism spectrum disorder: focus on Bdnf and Igf-1 -- The role of the oxytocin/arginine vasopressin system in animal models of autism spectrum disorder -- Extracerebral dysfunction in animal models of autism spectrum disorder -- Genetic and pharmacological reversibility of phenotypes in mouse models of autism spectrum disorder.

Autism spectrum disorder (ASD) affects approximately 1 % of the human population and is characterized by a core symptomatology including deficits in social interaction and repetitive patterns of behaviour plus various co-morbidities. Although a lot of progress has been made to uncover underlying causes and mechanisms throughout the last decade, we are still at the very beginning to understand this enormously complex neurodevelopmental condition. This special volume is focused on translational anatomy and cell biology of ASD. International experts from the field including several members of the EU-AIMS initiative launched by the European Union to develop novel treatments for ASD have contributed chapters on several topics covering all crucial aspects of translational ASD research with a special emphasis on ASD model systems including stem cells and animals. Primary objective is to clarify how anatomical and cell biological phenotypes of ASD will help to translate basic mechanisms to clinical practice and to efficiently treat affected individuals in the near future.

ISBN: 9783319524986$q(electronic bk.)

Standard No.: 10.1007/978-3-319-52498-6doiSubjects--Topical Terms:

785810
Autism spectrum disorders
--Molecular aspects.

LC Class. No.: RC553.A88

Dewey Class. No.: 616.85882

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