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The multiple inert gas elimination t...

Hopkins, Susan R.

The multiple inert gas elimination technique (MIGET)

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The multiple inert gas elimination technique (MIGET)by Susan R. Hopkins, Peter D. Wagner.
作者:	Hopkins, Susan R.
其他作者:	Wagner, Peter D.
出版者:	Boston, MA :Springer US :2017.
面頁冊數:	xiii, 329 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
標題:	Pulmonary gas exchange.
電子資源:	http://dx.doi.org/10.1007/978-1-4939-7441-2
ISBN:	9781493974412$q(electronic bk.)

The multiple inert gas elimination technique (MIGET)
Hopkins, Susan R.

The multiple inert gas elimination technique (MIGET)[electronic resource] /by Susan R. Hopkins, Peter D. Wagner. - Boston, MA :Springer US :2017. - xiii, 329 p. :ill. (some col.), digital ;24 cm. - Methods in physiology. - Methods in physiology..

Chapter 1: Introduction and history -- Chapter 2: MIGET: Basic Physiological Principles -- Chapter 3: Mathematical Underpinnings -- Chapter 4: Strengths and Limitations from a Mathematical Perspective -- Chapter 5: Physiological Information Content of MIGET -- Chapter 6: MIGET: Practical Aspect -- chapter 7: Review of the MIGET Literature.

This is the first book to bring together the history, theory, mathematical approach, measurement details and limitations of the Multiple Inert Gas Elimination Technique (MIGET) and a summary of the global literature on its application in health and disease over the last 40 years. Up to the early 1970's, and despite substantial research carried out by leaders in respiratory physiology, it was not possible to measure the most important and most complex component of gas exchange in the lung: ventilation/perfusion (VA/Q) heterogeneity. Building on that earlier research, MIGET was developed to overcome this large gap in our understanding of the most important function of the lung. Just as CT and MRI make use of multiple, simultaneous imaging views to reconstruct the underlying anatomy spatially, MIGET uses the simultaneous exchange of six inert gases with differing blood solubility to reconstruct the functional distribution of VA/Q ratios. While the basic physiological principle of MIGET is straightforward, using inert gas exchange data to construct the VA/Q distribution requires complicated mathematics along with the ability to simultaneously measure the exchange of six foreign gases present in just parts per million or less. This unique book is a valuable resource for anyone interested in how the lung works.

ISBN: 9781493974412$q(electronic bk.)

Standard No.: 10.1007/978-1-4939-7441-2doiSubjects--Topical Terms:

797969
Pulmonary gas exchange.

LC Class. No.: QP124

Dewey Class. No.: 612.22

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520 $a This is the first book to bring together the history, theory, mathematical approach, measurement details and limitations of the Multiple Inert Gas Elimination Technique (MIGET) and a summary of the global literature on its application in health and disease over the last 40 years. Up to the early 1970's, and despite substantial research carried out by leaders in respiratory physiology, it was not possible to measure the most important and most complex component of gas exchange in the lung: ventilation/perfusion (VA/Q) heterogeneity. Building on that earlier research, MIGET was developed to overcome this large gap in our understanding of the most important function of the lung. Just as CT and MRI make use of multiple, simultaneous imaging views to reconstruct the underlying anatomy spatially, MIGET uses the simultaneous exchange of six inert gases with differing blood solubility to reconstruct the functional distribution of VA/Q ratios. While the basic physiological principle of MIGET is straightforward, using inert gas exchange data to construct the VA/Q distribution requires complicated mathematics along with the ability to simultaneously measure the exchange of six foreign gases present in just parts per million or less. This unique book is a valuable resource for anyone interested in how the lung works.
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