國立高雄大學圖資館 |

語系: 繁體中文

說明(常見問題)

圖資館首頁

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Handbook of immunosenescencebasic un...

Fulop, Tamas.

Handbook of immunosenescencebasic understanding and clinical implications /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Handbook of immunosenescenceedited by Tamas Fulop ... [et al.].
其他題名:	basic understanding and clinical implications /
其他作者:	Fulop, Tamas.
出版者:	Cham :Springer International Publishing :2019.
面頁冊數:	xlix, 2879 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Immune systemAging.
電子資源:	https://doi.org/10.1007/978-3-319-99375-1
ISBN:	9783319993751$q(electronic bk.)

Handbook of immunosenescencebasic understanding and clinical implications /
Handbook of immunosenescencebasic understanding and clinical implications /[electronic resource] :edited by Tamas Fulop ... [et al.]. - 2nd ed. - Cham :Springer International Publishing :2019. - xlix, 2879 p. :ill., digital ;24 cm.

Methods and Models for Studying Immunosenescence -- Methods for studying human immunosenescence in tissues other than blood -- Mechanisms - Receptors and Signal Transduction -- Clinical Relevance in Disease States - Infection -- Modulation -- Nutrition.

Immunosenescence is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. We are poised to be in a position to translate these accumulated data into the clinical setting via better understanding of the contribution of immunosenescence to age-associated pathologies, and their prevention by appropriate interventions. This authoritative handbook seeks to encompass the current state of our knowledge on the multitude of those changes to immunity related to aging, with contributions from experts in the research and clinical areas. This book therefore considers methods and models for studying immunosenescence; cellular immunosenescence of T cells, B cells, neutrophils, antigen presenting cells, NK, NKT and stem cells; genetics; mechanisms including receptors and signal transduction; mitochondria; proteasome; cytokines; neuro-endocrine-immune networks; inflammation; thymus; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; modulation by nutrition, lipids, vaccination and the question "can interventions to influence immunosenescence be realistically proposed based on our current state of knowledge?".

ISBN: 9783319993751$q(electronic bk.)

Standard No.: 10.1007/978-3-319-99375-1doiSubjects--Topical Terms:

339292
Immune system
--Aging.

LC Class. No.: QR182 / .H363 2019

Dewey Class. No.: 616.079

Handbook of immunosenescencebasic understanding and clinical implications /
LDR:02734nmm a2200337 a 4500 001 558583
003 DE-He213
005 20191016150232.0
006 m d
007 cr nn 008maaau
008 191219s2019 gw s 0 eng d
020 $a 9783319993751$q(electronic bk.)
020 $a 9783319993737$q(paper)
024 7 $a 10.1007/978-3-319-99375-1 $2 doi
035 $a 978-3-319-99375-1
040 $a GP $c GP
041 0 $a eng
050 4 $a QR182 $b .H363 2019
072 7 $a MBGR $2 bicssc
072 7 $a MED000000 $2 bisacsh
072 7 $a MBGR $2 thema
082 0 4 $a 616.079 $2 23
090 $a QR182 $b .H236 2019
245 0 0 $a Handbook of immunosenescence $h [electronic resource] : $b basic understanding and clinical implications / $c edited by Tamas Fulop ... [et al.].
250 $a 2nd ed.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2019.
300 $a xlix, 2879 p. : $b ill., digital ; $c 24 cm.
505 0 $a Methods and Models for Studying Immunosenescence -- Methods for studying human immunosenescence in tissues other than blood -- Mechanisms - Receptors and Signal Transduction -- Clinical Relevance in Disease States - Infection -- Modulation -- Nutrition.
520 $a Immunosenescence is an imprecise term used to describe deleterious age-associated changes to immune parameters observed in all mammals studied so far. It represents a rapidly progressing science in the aging field, with a vertiginous volume of new data, knowledge and concepts concerning these changes. We are poised to be in a position to translate these accumulated data into the clinical setting via better understanding of the contribution of immunosenescence to age-associated pathologies, and their prevention by appropriate interventions. This authoritative handbook seeks to encompass the current state of our knowledge on the multitude of those changes to immunity related to aging, with contributions from experts in the research and clinical areas. This book therefore considers methods and models for studying immunosenescence; cellular immunosenescence of T cells, B cells, neutrophils, antigen presenting cells, NK, NKT and stem cells; genetics; mechanisms including receptors and signal transduction; mitochondria; proteasome; cytokines; neuro-endocrine-immune networks; inflammation; thymus; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; modulation by nutrition, lipids, vaccination and the question "can interventions to influence immunosenescence be realistically proposed based on our current state of knowledge?".
650 0 $a Immune system $x Aging. $3 339292
650 1 4 $a Biomedicine general. $3 273948
700 1 $a Fulop, Tamas. $3 339291
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
856 4 0 $u https://doi.org/10.1007/978-3-319-99375-1
950 $a Biomedical and Life Sciences (Springer-11642)