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Single-cell sequencing and methylati...

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Single-cell sequencing and methylationmethods and clinical applications /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Single-cell sequencing and methylationedited by Buwei Yu ... [et al.].
其他題名:	methods and clinical applications /
其他作者:	Yu, Buwei.
出版者:	Singapore :Springer Singapore :2020.
面頁冊數:	viii, 247 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	DNAMethylation.
電子資源:	https://doi.org/10.1007/978-981-15-4494-1
ISBN:	9789811544941$q(electronic bk.)

Single-cell sequencing and methylationmethods and clinical applications /
Single-cell sequencing and methylationmethods and clinical applications /[electronic resource] :edited by Buwei Yu ... [et al.]. - Singapore :Springer Singapore :2020. - viii, 247 p. :ill. (some col.), digital ;24 cm. - Advances in experimental medicine and biology,v.12550065-2598 ;. - Advances in experimental medicine and biology ;946..

Values of single-cell sequencing and methylation in molecular diagnosis and therapy -- Single-cell sequencing in human diseases -- Single-cell sequencing of T cell receptors: A perspective on the technological development and translational application -- DNA Methylation in pulmonary fibrosis -- Molecular regulation and clinical significance of caveolin-1 methylation in chronic lung diseases -- Research advances on DNA methylation in idiopathic pulmonary fibrosis -- DNA Methylation in Chronic Obstructive Pulmonary Disease -- Single cell sequencing: a new dimension in cancer diagnosis -- The Role of Methylation in the CpG Island of the ARHI Promoter Region in Cancers -- Clinical Significance of P16 Gene Methylation in Lung Cancer -- Application of single-cell RNA sequencing in pancreatic cancer and the endocrine pancreas -- Single Cell Sequencing in GU Malignancies -- PI3K Isoform-Selective Inhibitors in Cancer -- Single cell RNA sequencing in human disease: Renal, pancreatic, and viral diseases -- Single-cell sequencing in human genital infections -- PI3kinase Inhibitors in Thrombosis and Cardiovascular Disease -- Use of single-cell microfluidic technology towards therapeutic antibody discovery from single B cells.

With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.

ISBN: 9789811544941$q(electronic bk.)

Standard No.: 10.1007/978-981-15-4494-1doiSubjects--Topical Terms:

229553
DNA
--Methylation.

LC Class. No.: QP624.5.M46

Dewey Class. No.: 572.8645

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