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Flow chemistry in drug discovery

Alcazar, Jesus.

Flow chemistry in drug discovery

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Flow chemistry in drug discoveryedited by Jesus Alcazar, Antonio de la Hoz, Angel Diaz-Ortiz.
其他作者:	Alcazar, Jesus.
出版者:	Cham :Springer International Publishing :2021.
面頁冊數:	xxvii, 479 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Drug development.
電子資源:	https://doi.org/10.1007/978-3-030-85592-5
ISBN:	9783030855925$q(electronic bk.)

Flow chemistry in drug discovery
Flow chemistry in drug discovery[electronic resource] /edited by Jesus Alcazar, Antonio de la Hoz, Angel Diaz-Ortiz. - Cham :Springer International Publishing :2021. - xxvii, 479 p. :ill., digital ;24 cm. - Topics in medicinal chemistry,v. 381862-247X ;. - Topics in medicinal chemistry ;8..

Flow Chemistry in Drug Discovery: Challenges and Opportunities -- Green aspects of Flow Chemistry for Drug Discovery -- New process windows for synthesis of bioactive compounds -- Asymmetric catalysis in flow for Drug Discovery -- Organocatalysis in flow for Drug Discovery -- Biocatalysis in flow for Drug Discovery -- Photochemistry in flow for Drug Discovery -- Electrochemistry in flow for Drug Discovery -- Drug Discovery automation and library synthesis in flow -- Improved synthesis of bioactive molecules through Flow Chemistry -- Flash Chemistry in microsystems for Drug Discovery -- New biomass reagents for synthesis of bioactive compounds -- Flow Chemistry supporting access to Drug Discovery in Development countries.

This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R&D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development.

ISBN: 9783030855925$q(electronic bk.)

Standard No.: 10.1007/978-3-030-85592-5doiSubjects--Topical Terms:

190608
Drug development.

LC Class. No.: RM301.25 / .F56 2021

Dewey Class. No.: 615.19

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520 $a This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds. Prepared by expert contributors, the respective chapters cover not only fundamental methodologies and reactions, such as the application of catalysis, especially biocatalysis and organocatalysis; and non-conventional activation techniques, from photochemistry to electrochemistry; but also the development of new process windows, processes and reactions in drug synthesis. Particular attention is given to automatization and library synthesis, which are of great importance in the pharmaceutical industry. Readers will also find coverage on selected topics of general interest, such as how flow chemistry is contributing to drug discovery R&D in developing countries, and the green character of this enabling technology, for example in the production of raw materials for the pharmaceutical industry from waste. Given its scope, the book appeals to medicinal chemistry researchers working in academia and industry alike, as well as professionals involved in scale-up and drug development.
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