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Mixed-mode chromatographyprinciples,...

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Mixed-mode chromatographyprinciples, methods, and applications /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Mixed-mode chromatographyby Qian-Hong Wan.
其他題名:	principles, methods, and applications /
作者:	Wan, Qian-Hong.
出版者:	Singapore :Springer Singapore :2021.
面頁冊數:	xiii, 482 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Chromatographic analysis.
電子資源:	https://doi.org/10.1007/978-981-16-5485-5
ISBN:	9789811654855$q(electronic bk.)

Mixed-mode chromatographyprinciples, methods, and applications /
Wan, Qian-Hong.

Mixed-mode chromatographyprinciples, methods, and applications /[electronic resource] :by Qian-Hong Wan. - Singapore :Springer Singapore :2021. - xiii, 482 p. :ill. (some col.), digital ;24 cm.

Chapter 1.Historical Perspectives -- Chapter 2.Theoretical Background -- Chapter 3.Modes of Chromatographic Separation -- Chapter 4.Chromatographic Matrices -- Chapter 5.Ligand Design -- Chapter 6.Retention Mechanisms -- Chapter 7.Stationary Phases -- Chapter 8.Mobile Phases and Elution -- Chapter 9.Method Development -- Chapter 10.Applications in Biopharmaceutical Processing.

The book is about the technology and application of Mixed-mode chromatography (MMC) Unlike conventional single-mode HPLC, which resolves the analytes primarily based on their ionic or hydrophobic properties, MMC employs multifunctional stationary phases to exploit at least two modes of interactions (i.e., ionic and hydrophobic) with the analytes and as such often provides resolution that far exceeds that observed with a single-mode process. Over the past two decades, MMC has developed into an important analytical and purification tool in a number of applications in pharmaceutical and biotechnology industries. The technique has been used widely for the analyses of nucleic acids, amino acids, peptides, proteins, glycoproteins, carbohydrates, antibiotics, vaccines, and other products. The purpose of this book is to present a comprehensive survey of mixed-mode chromatography and is intended as a reference guide for graduate students and experienced scientists in pharmaceutical and biotechnology disciplines wishing to gain a deep understanding of this continuously evolving technology.

ISBN: 9789811654855$q(electronic bk.)

Standard No.: 10.1007/978-981-16-5485-5doiSubjects--Topical Terms:

193953
Chromatographic analysis.

LC Class. No.: QP519.9.C47 / W36 2021

Dewey Class. No.: 543.8

National Library of Medicine Call No.: QT 36.5

Mixed-mode chromatographyprinciples, methods, and applications /
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505 0 $a Chapter 1.Historical Perspectives -- Chapter 2.Theoretical Background -- Chapter 3.Modes of Chromatographic Separation -- Chapter 4.Chromatographic Matrices -- Chapter 5.Ligand Design -- Chapter 6.Retention Mechanisms -- Chapter 7.Stationary Phases -- Chapter 8.Mobile Phases and Elution -- Chapter 9.Method Development -- Chapter 10.Applications in Biopharmaceutical Processing.
520 $a The book is about the technology and application of Mixed-mode chromatography (MMC) Unlike conventional single-mode HPLC, which resolves the analytes primarily based on their ionic or hydrophobic properties, MMC employs multifunctional stationary phases to exploit at least two modes of interactions (i.e., ionic and hydrophobic) with the analytes and as such often provides resolution that far exceeds that observed with a single-mode process. Over the past two decades, MMC has developed into an important analytical and purification tool in a number of applications in pharmaceutical and biotechnology industries. The technique has been used widely for the analyses of nucleic acids, amino acids, peptides, proteins, glycoproteins, carbohydrates, antibiotics, vaccines, and other products. The purpose of this book is to present a comprehensive survey of mixed-mode chromatography and is intended as a reference guide for graduate students and experienced scientists in pharmaceutical and biotechnology disciplines wishing to gain a deep understanding of this continuously evolving technology.
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