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Single molecule science :from super-...
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Appasani, Krishnarao, (1959-)
Single molecule science :from super-resolution microscopy to DNA mapping and diagnostics /
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Single molecule science :edited by Krishnarao Appasani, Raghu Kiran Appasani ; foreword by Manfred Auer.
其他題名:
from super-resolution microscopy to DNA mapping and diagnostics /
其他作者:
Appasani, Krishnarao,
面頁冊數:
1 online resource (xxii, 147 pages) :illustrations (some color)
標題:
Molecular biologyTechnique.
電子資源:
https://doi.org/10.1017/9781108525909
ISBN:
9781108525909
Single molecule science :from super-resolution microscopy to DNA mapping and diagnostics /
Single molecule science :
from super-resolution microscopy to DNA mapping and diagnostics /edited by Krishnarao Appasani, Raghu Kiran Appasani ; foreword by Manfred Auer. - 1 online resource (xxii, 147 pages) :illustrations (some color)
Includes bibliographical references and index.
Part I: Super-Resolution Microscopy and Molecular Imaging Techniques to Probe Biology -- 1. Introduction on Single-Molecule Science -- 2. One Molecule, Two Molecules, Red Molecules, Blue Molecules: Methods for Quantifying Localization Microscopy Data -- 3. Multiscale Fluorescence Imaging -- 4. Long-Read Single-Molecule Optical Maps -- Part II: Protein Folding, Structure, Confirmation, and Dynamics -- 5. Single-Molecule Mechanics of Protein Nanomachines -- 6. Posttranslational Protein Translocation through Membranes at the Single-Molecule Level -- Part III: Mapping DNA Molecules at the Single-Molecule Level -- 7. Observing Dynamic States of Single-Molecule DNA and Proteins Using Atomic Force Microscope -- 8. Atomic Force Microscopy and Detecting a DNA Biomarker of a Few Copies without Amplification -- Part IV: Single-Molecule Biology to Study Gene Expression -- 9. Single-Molecule Detection in the Study of Gene Expression
"Single Molecule Science (SMS) has emerged from developing, using and combining technologies such as super-resolution microscopy, atomic force microscopy, and optical and magnetic tweezers, alongside sophisticated computational and modelling techniques. This comprehensive, edited volume brings together authoritative overviews of these methods from a biological perspective, and highlights how they can be used to observe and track individual molecules and monitor molecular interactions in living cells. Pioneers in this fast-moving field cover topics such as single molecule optical maps, nanomachines, and protein folding and dynamics. A particular emphasis is also given to mapping DNA molecules for diagnostic purposes, and the study of gene expression. With numerous illustrations, this book reveals how SMS has presented us with a new way of understanding life processes. A must-have for researchers and graduate students, as well as those working in industry, primarily in the areas of biophysics, biological imaging, genomics and structural biology"--
ISBN: 9781108525909
Source: cam 2200421 i 4500
LCCN: 2020041019Subjects--Topical Terms:
189145
Molecular biology
--Technique.
LC Class. No.: QH506 / .S5456 2022
Dewey Class. No.: 572.8/2
Single molecule science :from super-resolution microscopy to DNA mapping and diagnostics /
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Part I: Super-Resolution Microscopy and Molecular Imaging Techniques to Probe Biology -- 1. Introduction on Single-Molecule Science -- 2. One Molecule, Two Molecules, Red Molecules, Blue Molecules: Methods for Quantifying Localization Microscopy Data -- 3. Multiscale Fluorescence Imaging -- 4. Long-Read Single-Molecule Optical Maps -- Part II: Protein Folding, Structure, Confirmation, and Dynamics -- 5. Single-Molecule Mechanics of Protein Nanomachines -- 6. Posttranslational Protein Translocation through Membranes at the Single-Molecule Level -- Part III: Mapping DNA Molecules at the Single-Molecule Level -- 7. Observing Dynamic States of Single-Molecule DNA and Proteins Using Atomic Force Microscope -- 8. Atomic Force Microscopy and Detecting a DNA Biomarker of a Few Copies without Amplification -- Part IV: Single-Molecule Biology to Study Gene Expression -- 9. Single-Molecule Detection in the Study of Gene Expression
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