國立高雄大學圖資館 |

登入

回首頁

Features and management of acute and chronic neuro-covid

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Features and management of acute and chronic neuro-covidby Marco Cascella, Elvio De Blasio.
作者:	Cascella, Marco.
其他作者:	De Blasio, Elvio.
出版者:	Cham :Springer International Publishing :2022.
面頁冊數:	xix, 158 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	COVID-19 (Disease)Pathophysiology.
電子資源:	https://doi.org/10.1007/978-3-030-86705-8
ISBN:	9783030867058$q(electronic bk.)

Features and management of acute and chronic neuro-covid
Cascella, Marco.

Features and management of acute and chronic neuro-covid[electronic resource] /by Marco Cascella, Elvio De Blasio. - Cham :Springer International Publishing :2022. - xix, 158 p. :ill. (some col.), digital ;24 cm.

Introduction -- Part I. Pathophysiology of COVID-19-associated neurotoxicity -- An update on preclinical findings -- Ongoing clinical investigations -- Perspectives -- Part II. Clinical manifestations of acute neurotoxicity -- Clinical features -- CNS complications -- PNS complications -- Diagnosis -- Management -- Perspectives -- Part III. Neurological and psychiatric sequelae in COVID-19 survivors -- Clinical features -- Neurological late complications -- psychological and psychiatric sequelae -- Diagnosis -- Tools -- The role of imaging -- Preventive strategies -- Social and economic impact -- Multidisciplinary management -- Perspectives.

This book underlines how COVID-19 is a multisystem inflammatory disease and how its pathophysiology can predispose to an increased risk of neurological issues. Several scientific pieces of evidence showes the mechanisms underlying the neuroinvasive capacity of the SARS-CoV-2 through direct viral damage and indirect processes entering the CNS by different routes including the vasculature, the olfactory and trigeminal nerves, the cerebrospinal fluid, and the lymphatic system inducing a direct neurotoxicity. Furthermore, the pro-inflammatory cytokine storm and oxidative stress can induce microglial activation and damage to the blood-brain barrier, culminating in widespread neuroinflammatory process. This acute neurotoxicity is clinically expressed as anosmia and ageusia, headache, nausea and vomiting, but other neurologic manifestations such as acute cerebrovascular diseases, consciousness impairment due to encephalitis, and meningitis are also described. The PNS can also be affected by infectious damage and clinical manifestations including Guillain-Barre syndrome, polyneuritis cranialis, and Miller Fisher Syndrome. A special issue concerns the neurocognitive dysfunction and altered consciousness manifested as delirium, agitation and confusion. Non-specific symptoms such as dizziness, seizures can accompany clinical pictures. Regardless of the admission diagnosis, a high percentage of patients discharged from ICUs develop disabilities affecting physical, cognitive and psychological activities. The symptoms such as asthenia, memory disturbances, depression, sleep disturbances, anxiety, and Post-traumatic stress disorder (PTSD), configure the so-called Post-intensive Care Syndrome (PICS) Multimodal management during the ICU stay and implementation of follow-up programs at patient discharge can reduce the incidence of this syndrome, improving the quality of life of surviving patients. In this complex scenario, a careful clinical approach through reliable diagnostic tools, and epidemiological studies aimed at evaluating the dimensions of the problem also in economic terms, is urgently needed. This book represents a valuable aid for all those healthcare professionals (intensivists, neurologist and psychiatrists, as well) involved in the management of these critically ill patients.

ISBN: 9783030867058$q(electronic bk.)

Standard No.: 10.1007/978-3-030-86705-8doiSubjects--Topical Terms:

918065
COVID-19 (Disease)
--Pathophysiology.

LC Class. No.: RA644.C67 / C37 2022

Dewey Class. No.: 616.2414

Features and management of acute and chronic neuro-covid
LDR:03965nmm a2200325 a 4500 001 618410
003 DE-He213
005 20211127162931.0
006 m d
007 cr nn 008maaau
008 221025s2022 sz s 0 eng d
020 $a 9783030867058$q(electronic bk.)
020 $a 9783030867041$q(paper)
024 7 $a 10.1007/978-3-030-86705-8 $2 doi
035 $a 978-3-030-86705-8
040 $a GP $c GP
041 0 $a eng
050 4 $a RA644.C67 $b C37 2022
072 7 $a MMKL $2 bicssc
072 7 $a MED015000 $2 bisacsh
072 7 $a MKPL $2 thema
082 0 4 $a 616.2414 $2 23
090 $a RA644.C67 $b C336 2022
100 1 $a Cascella, Marco. $3 753749
245 1 0 $a Features and management of acute and chronic neuro-covid $h [electronic resource] / $c by Marco Cascella, Elvio De Blasio.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2022.
300 $a xix, 158 p. : $b ill. (some col.), digital ; $c 24 cm.
505 0 $a Introduction -- Part I. Pathophysiology of COVID-19-associated neurotoxicity -- An update on preclinical findings -- Ongoing clinical investigations -- Perspectives -- Part II. Clinical manifestations of acute neurotoxicity -- Clinical features -- CNS complications -- PNS complications -- Diagnosis -- Management -- Perspectives -- Part III. Neurological and psychiatric sequelae in COVID-19 survivors -- Clinical features -- Neurological late complications -- psychological and psychiatric sequelae -- Diagnosis -- Tools -- The role of imaging -- Preventive strategies -- Social and economic impact -- Multidisciplinary management -- Perspectives.
520 $a This book underlines how COVID-19 is a multisystem inflammatory disease and how its pathophysiology can predispose to an increased risk of neurological issues. Several scientific pieces of evidence showes the mechanisms underlying the neuroinvasive capacity of the SARS-CoV-2 through direct viral damage and indirect processes entering the CNS by different routes including the vasculature, the olfactory and trigeminal nerves, the cerebrospinal fluid, and the lymphatic system inducing a direct neurotoxicity. Furthermore, the pro-inflammatory cytokine storm and oxidative stress can induce microglial activation and damage to the blood-brain barrier, culminating in widespread neuroinflammatory process. This acute neurotoxicity is clinically expressed as anosmia and ageusia, headache, nausea and vomiting, but other neurologic manifestations such as acute cerebrovascular diseases, consciousness impairment due to encephalitis, and meningitis are also described. The PNS can also be affected by infectious damage and clinical manifestations including Guillain-Barre syndrome, polyneuritis cranialis, and Miller Fisher Syndrome. A special issue concerns the neurocognitive dysfunction and altered consciousness manifested as delirium, agitation and confusion. Non-specific symptoms such as dizziness, seizures can accompany clinical pictures. Regardless of the admission diagnosis, a high percentage of patients discharged from ICUs develop disabilities affecting physical, cognitive and psychological activities. The symptoms such as asthenia, memory disturbances, depression, sleep disturbances, anxiety, and Post-traumatic stress disorder (PTSD), configure the so-called Post-intensive Care Syndrome (PICS) Multimodal management during the ICU stay and implementation of follow-up programs at patient discharge can reduce the incidence of this syndrome, improving the quality of life of surviving patients. In this complex scenario, a careful clinical approach through reliable diagnostic tools, and epidemiological studies aimed at evaluating the dimensions of the problem also in economic terms, is urgently needed. This book represents a valuable aid for all those healthcare professionals (intensivists, neurologist and psychiatrists, as well) involved in the management of these critically ill patients.
650 0 $a COVID-19 (Disease) $x Pathophysiology. $3 918065
650 0 $a Neurotoxicology. $3 302504
650 0 $a Neurologic manifestations of general diseases. $3 277789
650 1 4 $a Intensive / Critical Care Medicine. $3 274888
650 2 4 $a Neurology. $3 211583
650 2 4 $a Psychiatry. $3 201470
650 2 4 $a Public Health. $3 320661
700 1 $a De Blasio, Elvio. $3 918064
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-3-030-86705-8
950 $a Medicine (SpringerNature-11650)