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Pediatric cancer therapeutics development

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Pediatric cancer therapeutics developmentedited by Jorge DiMartino, Gregory H. Reaman, Franklin O. Smith.
其他作者:	DiMartino, Jorge.
出版者:	Cham :Springer International Publishing :2022.
面頁冊數:	vi, 181 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	Cancer in childrenTreatment.
電子資源:	https://doi.org/10.1007/978-3-031-06357-2
ISBN:	9783031063572$q(electronic bk.)

Pediatric cancer therapeutics development
Pediatric cancer therapeutics development[electronic resource] /edited by Jorge DiMartino, Gregory H. Reaman, Franklin O. Smith. - Cham :Springer International Publishing :2022. - vi, 181 p. :ill., digital ;24 cm. - Pediatric oncology,2191-0812. - Pediatric oncology..

History of Drug Development -- Target Identification/Validation and Drug Discovery -- Non-Clinical Toxicology -- Study Design and Biostatistics -- Personalized Medicine and Its Impact on Study Design -- Gene and Cellular Therapy -- The Pharma/Biotech Model for Drug Development -- Clinical Research Organizations -- Role of Patients and Advocates in Cancer Therapeutics -- Development -- International Regulatory Agencies -- Ethical Considerations in Cancer Therapeutics Development -- Future Directions: Jorge DiMartino.

This book provides a comprehensive overview of the scientific, medical, regulatory, and economic considerations associated with the discovery, development, and delivery of novel therapeutics for children with cancer. Co-authored by a diverse team from academic, government, and industry backgrounds, the book describes the steps in the process from the identification of a promising therapeutic target to the evaluation of drug candidates in the various phases of clinical testing and regulatory review. Throughout, special emphasis is placed on the unique biology of pediatric malignancies and the medical and social needs of children and their families. In providing a firm grounding in the drug development process, the book will be of value to all with an interest in how medicines currently used to treat pediatric cancer were made available. This includes trainees as well as established practitioners and others participating in translational and clinical research in the academic setting.

ISBN: 9783031063572$q(electronic bk.)

Standard No.: 10.1007/978-3-031-06357-2doiSubjects--Topical Terms:

727620
Cancer in children
--Treatment.

LC Class. No.: RC281.C4

Dewey Class. No.: 618.9299406

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520 $a This book provides a comprehensive overview of the scientific, medical, regulatory, and economic considerations associated with the discovery, development, and delivery of novel therapeutics for children with cancer. Co-authored by a diverse team from academic, government, and industry backgrounds, the book describes the steps in the process from the identification of a promising therapeutic target to the evaluation of drug candidates in the various phases of clinical testing and regulatory review. Throughout, special emphasis is placed on the unique biology of pediatric malignancies and the medical and social needs of children and their families. In providing a firm grounding in the drug development process, the book will be of value to all with an interest in how medicines currently used to treat pediatric cancer were made available. This includes trainees as well as established practitioners and others participating in translational and clinical research in the academic setting.
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