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Obesity, diabetes and inflammationmolecular mechanisms and clinical management /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Obesity, diabetes and inflammationedited by Dimiter Avtanski, Leonid Poretsky.
其他題名:	molecular mechanisms and clinical management /
其他作者:	Avtanski, Dimiter.
出版者:	Cham :Springer International Publishing :2023.
面頁冊數:	viii, 234 p. :ill., digital ;24 cm.
Contained By:	Springer Nature eBook
標題:	ObesityComplications.
電子資源:	https://doi.org/10.1007/978-3-031-39721-9
ISBN:	9783031397219$q(electronic bk.)

Obesity, diabetes and inflammationmolecular mechanisms and clinical management /
Obesity, diabetes and inflammationmolecular mechanisms and clinical management /[electronic resource] :edited by Dimiter Avtanski, Leonid Poretsky. - Cham :Springer International Publishing :2023. - viii, 234 p. :ill., digital ;24 cm. - Contemporary endocrinology,2523-3793. - Contemporary endocrinology..

Inflammation: Pathogenesis and Biological Markers -- Obesity and Inflammation -- Inflammation and Diabetes Mellitus -- Diabetes, Obesity, and Oxidative stress -- Advanced Glycation End-Products and Diabetes -- Genetic and Epigenetic Basis of Obesity-Induced Inflammation and Diabetes -- Inflammation and Vascular Pathologies -- Environmental and Lifestyle Factors Influencing Inflammation and Type 2 Diabetes Onset -- Inflammation in Pregnant Women with Obesity and Gestational Diabetes -- Potential Pharmaceutical and Non-Pharmaceutical Approaches to Obesity and Diabetes: Focus on Inflammation.

Obesity is a worldwide epidemic that affects half a billion people. It has been estimated that, if current trends continue, by 2050, 60% of men and 50% of women worldwide will be obese. Hypertrophy and hyperplasia of white adipose tissue caused by overweight and obesity lead to a chronic inflammatory state, which results in impaired insulin sensitivity and the development of diabetes. Currently, the number of people affected by diabetes globally exceeds 400 million (rising more rapidly in low- and middle-income countries) In 2019, diabetes was the ninth leading cause of mortality, with an estimated 1.5 million direct deaths. This book provides a comprehensive overview of the relationship between inflammation, obesity, and diabetes. It focuses on the pathogenesis and biological mechanisms of obesity, the interaction between adipose tissue and the immune system, the role of genetic and environmental factors, the progression of cardiovascular complications, and the association of obesity and inflammation with type 1 and type 2 diabetes, as well as gestational diabetes. This volume also includes practical recommendations for preventing and managing these conditions using both lifestyle modifications and pharmacological interventions. Written by experts in the field, Obesity, Diabetes and Inflammation: Molecular Mechanisms and Clinical Management addresses the role of inflammation in both obesity and diabetes, its effect on vascular and non-vascular pathologies, oxidative stress, genetics, and epigenetics. This text aims to be a valuable resource for researchers, clinicians, and students of medicine at all levels.

ISBN: 9783031397219$q(electronic bk.)

Standard No.: 10.1007/978-3-031-39721-9doiSubjects--Topical Terms:

281111
Obesity
--Complications.

LC Class. No.: RC628

Dewey Class. No.: 616.398

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520 $a Obesity is a worldwide epidemic that affects half a billion people. It has been estimated that, if current trends continue, by 2050, 60% of men and 50% of women worldwide will be obese. Hypertrophy and hyperplasia of white adipose tissue caused by overweight and obesity lead to a chronic inflammatory state, which results in impaired insulin sensitivity and the development of diabetes. Currently, the number of people affected by diabetes globally exceeds 400 million (rising more rapidly in low- and middle-income countries) In 2019, diabetes was the ninth leading cause of mortality, with an estimated 1.5 million direct deaths. This book provides a comprehensive overview of the relationship between inflammation, obesity, and diabetes. It focuses on the pathogenesis and biological mechanisms of obesity, the interaction between adipose tissue and the immune system, the role of genetic and environmental factors, the progression of cardiovascular complications, and the association of obesity and inflammation with type 1 and type 2 diabetes, as well as gestational diabetes. This volume also includes practical recommendations for preventing and managing these conditions using both lifestyle modifications and pharmacological interventions. Written by experts in the field, Obesity, Diabetes and Inflammation: Molecular Mechanisms and Clinical Management addresses the role of inflammation in both obesity and diabetes, its effect on vascular and non-vascular pathologies, oxidative stress, genetics, and epigenetics. This text aims to be a valuable resource for researchers, clinicians, and students of medicine at all levels.
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